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Protein

40S ribosomal protein S6

Gene

RPS6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal proteinUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S6UniRule annotation
Gene namesi
Name:RPS6Imported
ORF Names:hCG_1741512Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34844.

Expressioni

Gene expression databases

BgeeiENSG00000137154.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000369757.

Structurei

3D structure databases

SMRiA2A3R6. Positions 1-230.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili203 – 23735Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the ribosomal protein S6e family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1646. Eukaryota.
COG2125. LUCA.
HOVERGENiHBG011441.
KOiK02991.
OMAiEGKKERF.
OrthoDBiEOG091G089B.
PhylomeDBiA2A3R6.

Family and domain databases

InterProiIPR014401. Ribosomal_S6_euk.
IPR001377. Ribosomal_S6e.
IPR018282. Ribosomal_S6e_CS.
[Graphical view]
PANTHERiPTHR11502. PTHR11502. 1 hit.
PfamiPF01092. Ribosomal_S6e. 1 hit.
[Graphical view]
PIRSFiPIRSF002129. Ribosom_S6_euk. 1 hit.
SMARTiSM01405. Ribosomal_S6e. 1 hit.
[Graphical view]
PROSITEiPS00578. RIBOSOMAL_S6E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2A3R6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV
60 70 80 90 100
RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC
110 120 130 140 150
IVDANLSVLN LVIVKKGEKD IPGLTDTTVP RRLGPKRASR IRKLFNLSKE
160 170 180 190 200
DDVRQYVVRK PLNKEGKKPR TKAPKIQRLV TPRVLQHKRR RIALKKQRTK
210 220 230 240
KNKEEAAEYA KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS TSKSESSQK
Length:249
Mass (Da):28,681
Last modified:February 20, 2007 - v1
Checksum:iA61E435884E636AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291517 mRNA. Translation: BAF84206.1.
AK311861 mRNA. Translation: BAG34802.1.
CH471071 Genomic DNA. Translation: EAW58641.1.
RefSeqiNP_001001.2. NM_001010.2.
UniGeneiHs.408073.

Genome annotation databases

GeneIDi6194.
KEGGihsa:6194.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291517 mRNA. Translation: BAF84206.1.
AK311861 mRNA. Translation: BAG34802.1.
CH471071 Genomic DNA. Translation: EAW58641.1.
RefSeqiNP_001001.2. NM_001010.2.
UniGeneiHs.408073.

3D structure databases

SMRiA2A3R6. Positions 1-230.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000369757.

Protocols and materials databases

DNASUi6194.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6194.
KEGGihsa:6194.

Organism-specific databases

CTDi6194.
PharmGKBiPA34844.

Phylogenomic databases

eggNOGiKOG1646. Eukaryota.
COG2125. LUCA.
HOVERGENiHBG011441.
KOiK02991.
OMAiEGKKERF.
OrthoDBiEOG091G089B.
PhylomeDBiA2A3R6.

Miscellaneous databases

ChiTaRSiRPS6. human.
GenomeRNAii6194.

Gene expression databases

BgeeiENSG00000137154.

Family and domain databases

InterProiIPR014401. Ribosomal_S6_euk.
IPR001377. Ribosomal_S6e.
IPR018282. Ribosomal_S6e_CS.
[Graphical view]
PANTHERiPTHR11502. PTHR11502. 1 hit.
PfamiPF01092. Ribosomal_S6e. 1 hit.
[Graphical view]
PIRSFiPIRSF002129. Ribosom_S6_euk. 1 hit.
SMARTiSM01405. Ribosomal_S6e. 1 hit.
[Graphical view]
PROSITEiPS00578. RIBOSOMAL_S6E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA2A3R6_HUMAN
AccessioniPrimary (citable) accession number: A2A3R6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: September 7, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.