A2A259 (A2A259_MOUSE) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 47.
History...
Names and origin
| Protein names | Submitted name: Polycystic kidney disease 2-like 1 EMBL BAF45380.1 Submitted name: Protein Pkd2l1 Ensembl ENSMUSP00000045675 | ||||
| Gene names |
| ||||
| Organism | Mus musculus (Mouse) [Reference proteome] | ||||
| Taxonomic identifier | 10090 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus![]() |
Protein attributes
| Sequence length | 760 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
Ontologies
| Keywords | |
|---|---|
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | cellular response to acidity Inferred from direct assay PubMed 16891422. Source: BHF-UCL detection of chemical stimulus involved in sensory perception of sour tasteInferred from direct assay PubMed 16891422. Source: BHF-UCL |
| Cellular_component | endoplasmic reticulum Inferred from direct assay PubMed 15548533. Source: MGI plasma membraneInferred from physical interaction PubMed 15548533. Source: MGI |
| Molecular_function | calcium ion binding Inferred from direct assay PubMed 20408813. Source: BHF-UCL calcium-activated potassium channel activityInferred from electronic annotation. Source: Compara cation channel activityInferred from physical interaction PubMed 15548533. Source: MGI sodium channel activityInferred from electronic annotation. Source: Compara |
| Complete GO annotation... | |
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor." Ishimaru Y., Inada H., Kubota M., Zhuang H., Tominaga M., Matsunami H. Proc. Natl. Acad. Sci. U.S.A. 103:12569-12574(2006) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAF45380.1. |
| [2] | Ishimaru Y. Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6 EMBL BAF45380.1. |
| [3] | "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000045675. |
| [4] | Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000045675. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AC125101 Genomic DNA. No translation available. AB290927 mRNA. Translation: BAF45380.1. |
| IPI | IPI00776115. |
| RefSeq | NP_852087.2. NM_181422.3. |
| UniGene | Mm.308481. |
3D structure databases | |
| SMR | A2A259. Positions 597-672, 698-739. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| Ensembl | ENSMUST00000042026; ENSMUSP00000045675; ENSMUSG00000037578. |
| GeneID | 329064. |
| KEGG | mmu:329064. |
| UCSC | uc008hpm.2. mouse. |
Organism-specific databases | |
| CTD | 9033. |
| MGI | MGI:1352448. Pkd2l1. |
Phylogenomic databases | |
| eggNOG | NOG325704. |
| GeneTree | ENSGT00700000104221. |
| HOGENOM | HOG000230858. |
| HOVERGEN | HBG014945. |
| InParanoid | A2A259. |
| KO | K04990. |
| OMA | GFHIFRT. |
| OrthoDB | EOG4D52X2. |
Gene expression databases | |
| Genevestigator | A2A259. |
Family and domain databases | |
| Gene3D | 1.10.238.10. 1 hit. |
| InterPro | IPR011992. EF-hand-like_dom. IPR002048. EF_hand_dom. IPR013122. PKD1_2_channel. IPR003915. PKD_2. [Graphical view] |
| Pfam | PF08016. PKD_channel. 1 hit. [Graphical view] |
| PRINTS | PR01433. POLYCYSTIN2. |
| PROSITE | PS50222. EF_HAND_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 398558. |
| SOURCE | Search... |
Entry information
| Entry name | A2A259_MOUSE | ||||||||
| Accession | Primary (citable) accession number: A2A259 | ||||||||
| Entry history |
| ||||||||
| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with

