A2A136 (A2A136_9BACL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Catalase RuleBase RU000498
EC=1.11.1.6 RuleBase RU000498

Gene names

Name:

ektA EMBL BAF45371.1

Organism

Exiguobacterium oxidotolerans EMBL BAF45371.1

Taxonomic identifier

223958 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillales incertae sedis › Bacillales Family XII. Incertae Sedis › Exiguobacterium

Protein attributes

Sequence length	491 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	2 H2O2 = O2 + 2 H2O. RuleBase RU000498
Sequence similarities	Belongs to the catalase family. RuleBase RU000498

Ontologies

Keywords
Biological process	Hydrogen peroxide RuleBase RU000498
Ligand	Heme RuleBase RU000498 PDB 2J2M Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	3D-structure PDB 2J2M
Gene Ontology (GO)
Biological_process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	339	1	Iron (heme axial ligand) PDB 2J2M

Sequences

	Sequence		Length	Mass (Da)
	A2A136 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 024092394EB49591	FASTA	491	56,523
	10 20 30 40 50 60 MNENEKKLTT NQGVPIGDNQ NSRTAGRRGP TLLEDYQLIE KIAHFDRERV PERVVHARGF 70 80 90 100 110 120 GAHGVFKVKN SMKKYTKAAF LQEEGTEVPV FARFSTVIHG THSPETLRDP RGFSVKFYTE 130 140 150 160 170 180 EGNWDFVGNN LPVFFIRDAM KFPDMVHSLK PDPRTNIQDP DRYWDFMTLR PESTNMLMHI 190 200 210 220 230 240 FTDEGIPASY RKMRGSSVHS FKWVNAHGNT VYIKLRWVPK EGVHNLSADE ATEVQGKDFN 250 260 270 280 290 300 HASNDTFQAI ENGDFPEWDL FVQVLDPADV ENFDFDPLDA TKDWFEDVIP FQHVGTMTLN 310 320 330 340 350 360 KNVDNYFAET ESVGFNPGVL VPGMLPSEDK LLQGRLFSYS DTQRHRIGPN YQQLPINCPF 370 380 390 400 410 420 AQVNNYQRDG AMPFKQQTSS VNYEPNRYQD EPKQTPEYTE DTQPLHDDIH GRLEIEKTNN 430 440 450 460 470 480 FGQAGEVYRR MTEEEQMALL NNLVNDLQQV RHENTVLLAI CNFYRADASL GEKLSEALNV 490 DIKPFLQQMQ K

References

[1]

"Relationship between the size of the bottleneck 15 A from iron in the main channel and the reactivity of catalase corresponding to the molecular size of substrates." Hara I., Ichise N., Kojima K., Kondo H., Ohgiya S., Matsuyama H., Yumoto I. Biochemistry 46:11-22(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AB266484 Genomic DNA. Translation: BAF45371.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2J2M	X-ray	2.40	A/B/C/D	1-491	[»]

ProteinModelPortal

A2A136.

SMR

A2A136. Positions 6-485.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.40.180.10. 1 hit.

InterPro

IPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]

PANTHER

PTHR11465. PTHR11465. 1 hit.

Pfam

PF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]

PIRSF

PIRSF038928. Catalase_clade1-3. 1 hit.

PRINTS

PR00067. CATALASE.

SMART

SM01060. Catalase. 1 hit.
[Graphical view]

SUPFAM

SSF56634. Catalase_N. 1 hit.

PROSITE

PS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

A2A136.

Entry information

Entry name

A2A136_9BACL

Accession

Primary (citable) accession number: A2A136

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	March 6, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)