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A2A114 (A2A114_NEOCA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:AMA1 EMBL BAF45372.1
OrganismNeospora caninum (Coccidian parasite) EMBL BAF45372.1
Taxonomic identifier29176 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeNeospora

Protein attributes

Sequence length564 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Technical term3D-structure PDB 4APL
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmembrane

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A2A114 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: F2E5FA8F903E0F9E

FASTA56462,813
        10         20         30         40         50         60 
MGSWRRERPA RPSDQQWITE WRQIGIVGVA ILLVLVAESS LLATGINPKT RSGGSQTLSA 

        70         80         90        100        110        120 
STPQNPFQTP ELKAFLERYN VTLHHQSGVN VDLGQDKEVD GKLYREAAGL CPVWGKYIQL 

       130        140        150        160        170        180 
HQPNRPPYKN NFLEDIPTEA EYQKSGNPLP GGFNMNFVTP AGQRISPYPM ELLEKSSKIK 

       190        200        210        220        230        240 
ASTELGKCAE FAYKTTAMDK SNQATQYRYP FVYDSKRRLC YILSVSMQRM EGSKYCSTND 

       250        260        270        280        290        300 
DPVNLTWYCF EPQKSPTANH NLIFGSAYVG KDPDAFLTKC PNQALKGYRF GHWTNGRCHD 

       310        320        330        340        350        360 
YTELADSWIE AVDSKAQCWV KTFTNDEVAS DQPRTYPLTS QHSWNDWWPV HEKDQPHSGG 

       370        380        390        400        410        420 
DGRNYGFFYF DSNGKGKCAL SHKAPDCLVS DSKAVSYTAL GSLSEETPDI IIPSNPSVNP 

       430        440        450        460        470        480 
STPDEALQCR SSEFPETFGS CDVQACKRQK TSCVGGQIQS TSVDCTAEEQ NDCGSNTALI 

       490        500        510        520        530        540 
AGMAIGGVLI MGLLAGSGYY YSKRLNTNQG VPAVDHDHEF QTQRNAQKKR PSDLMQEAEP 

       550        560 
SFWDEAEENI DQSGETQVLV EGDY 

« Hide

References

[1]"Apical membrane antigen 1 is a cross-reactive antigen between Neospora caninum and Toxoplasma gondii, and the anti-NcAMA1 antibody inhibits host cell invasion by both parasites."
Zhang H., Compaore M.K., Lee E.G., Liao M., Zhang G., Sugimoto C., Fujisaki K., Nishikawa Y., Xuan X.
Mol. Biochem. Parasitol. 151:205-212(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: NC-1 EMBL BAF45372.1.
[2]"Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion."
Tonkin M.L., Crawford J., Lebrun M.L., Boulanger M.J.
Protein Sci. 22:114-127(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 59-478.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB265823 mRNA. Translation: BAF45372.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4APLX-ray2.90A/B/D/E59-478[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR003298. Apmem_Ag1.
[Graphical view]
PfamPF02430. AMA-1. 2 hits.
[Graphical view]
PRINTSPR01361. MEROZOITESA.
SMARTSM00815. AMA-1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA2A114_NEOCA
AccessionPrimary (citable) accession number: A2A114
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 1, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)