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Protein
Submitted name:

Tubulin-binding cofactor B

Gene

TBCB

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cytoplasmic microtubule organization Source: FlyBase
  • establishment of apical/basal cell polarity Source: FlyBase
  • oocyte axis specification Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Tubulin-binding cofactor BImported
Gene namesi
Name:TBCBImported
ORF Names:CG11242Imported, Dmel_CG11242Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0034451. TBCB.

Subcellular locationi

GO - Cellular componenti

  • cell cortex Source: FlyBase
  • centrosome Source: FlyBase
  • cytoplasm Source: FlyBase
  • mitotic spindle Source: FlyBase
  • nucleus Source: FlyBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA1ZBM2.
PRIDEiA1ZBM2.

Expressioni

Gene expression databases

BgeeiFBgn0034451.
GenevisibleiA1ZBM2. DM.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0085690.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KJRNMR-A8-92[»]
ProteinModelPortaliA1ZBM2.
SMRiA1ZBM2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA1ZBM2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini182 – 224CAP-GlyInterPro annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili129 – 152Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3206. Eukaryota.
ENOG410YKGB. LUCA.
GeneTreeiENSGT00860000133787.
InParanoidiA1ZBM2.
KOiK17262.
OMAiFDSAPVE.
OrthoDBiEOG091G0M22.
PhylomeDBiA1ZBM2.

Family and domain databases

Gene3Di2.30.30.190. 1 hit.
InterProiIPR000938. CAP-Gly_domain.
IPR029071. Ubiquitin-rel_dom.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamiPF01302. CAP_GLY. 1 hit.
PF14560. Ubiquitin_2. 1 hit.
[Graphical view]
SMARTiSM01052. CAP_GLY. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF74924. SSF74924. 1 hit.
PROSITEiPS00845. CAP_GLY_1. 1 hit.
PS50245. CAP_GLY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1ZBM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTIIETGKS DFIKVNVSNS HNDAVAFEVK LAKDLTVAQL KTKLEILTGG
60 70 80 90 100
CAGTMKVQVF KGDTCVSTMD NNDAQLGYYA NSDGLRLHVV DSFATFSFDS
110 120 130 140 150
APVEKFELSK DQYEQRTDSV RNYLKINRMG KYNDEEMQQA EEKKRLQAEE
160 170 180 190 200
IQKRAELCVL GGRCEVTVPG NPTRRGTIRY NGPLEGKSGH FIGVEYDEPL
210 220 230 240
GKNNGSFGGK AYFTCAPNYG GFVSPLSVTV GDFPPEDFNM DDEL
Length:244
Mass (Da):26,974
Last modified:February 6, 2007 - v1
Checksum:i2D8C913FA59E8399
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF57546.1.
RefSeqiNP_611425.1. NM_137581.4.
UniGeneiDm.19962.

Genome annotation databases

EnsemblMetazoaiFBtr0086502; FBpp0085690; FBgn0034451.
GeneIDi37244.
KEGGidme:Dmel_CG11242.
UCSCiCG11242-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF57546.1.
RefSeqiNP_611425.1. NM_137581.4.
UniGeneiDm.19962.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KJRNMR-A8-92[»]
ProteinModelPortaliA1ZBM2.
SMRiA1ZBM2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0085690.

Proteomic databases

PaxDbiA1ZBM2.
PRIDEiA1ZBM2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0086502; FBpp0085690; FBgn0034451.
GeneIDi37244.
KEGGidme:Dmel_CG11242.
UCSCiCG11242-RA. d. melanogaster.

Organism-specific databases

CTDi1155.
FlyBaseiFBgn0034451. TBCB.

Phylogenomic databases

eggNOGiKOG3206. Eukaryota.
ENOG410YKGB. LUCA.
GeneTreeiENSGT00860000133787.
InParanoidiA1ZBM2.
KOiK17262.
OMAiFDSAPVE.
OrthoDBiEOG091G0M22.
PhylomeDBiA1ZBM2.

Miscellaneous databases

EvolutionaryTraceiA1ZBM2.
GenomeRNAii37244.

Gene expression databases

BgeeiFBgn0034451.
GenevisibleiA1ZBM2. DM.

Family and domain databases

Gene3Di2.30.30.190. 1 hit.
InterProiIPR000938. CAP-Gly_domain.
IPR029071. Ubiquitin-rel_dom.
IPR000626. Ubiquitin_dom.
[Graphical view]
PfamiPF01302. CAP_GLY. 1 hit.
PF14560. Ubiquitin_2. 1 hit.
[Graphical view]
SMARTiSM01052. CAP_GLY. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
SSF74924. SSF74924. 1 hit.
PROSITEiPS00845. CAP_GLY_1. 1 hit.
PS50245. CAP_GLY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA1ZBM2_DROME
AccessioniPrimary (citable) accession number: A1ZBM2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 30, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.