Unreviewed, UniProtKB/TrEMBL A1ZAW3 (A1ZAW3_DROME)

Names and origin

Protein names

Submitted name:
    RhoGAP54D, isoform A EMBL AAF57827.2

Gene names

Name:	RhoGAP54D FlyBase FBgn0034249
ORF Names:	Dmel_CG6477 EMBL AAF57827.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1004 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 1 Rho-GAP domain. Spearmint SPM000198

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1ZAW3-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 4E3688FCC10C3178	FASTA	1,004	110,662
	10 20 30 40 50 60 MEATMDTDHA NLNDFRDRDL ATRMRRCNYE KYKSLVRMHL SFELELNTDE FDLPCHEIVY 70 80 90 100 110 120 EDKGKLKKWN RLSKKHRLGH GAAATSCAAG SASKSVGNSP TETLQQQIDP GFLMHLQELK 130 140 150 160 170 180 EFLMLEKNLT QEGLFRKAGA VSRQNELRMH IQHDKPLNLE LAGFSAHDCA TVFKGFLSEL 190 200 210 220 230 240 PEPLLTDAHY PAHLQIAPLC QALNGQTTAT AERQQHLLNS VQLLLLLLPE EHRELLQHII 250 260 270 280 290 300 EMLHAVAKHE KSNKMSADNL ATLFTPHLIC PRQLPPEVLH YQAKKMSSIV TYMIVRGLDI 310 320 330 340 350 360 FEVPGKLSTD IRAYFLERKR KKTMSPEQTL DESISDVSTV NTVYTFVDRA ATAAATNTNN 370 380 390 400 410 420 TDTELAQLYA HIQSMPESSK KRRLIKQFNK QNGQGTPLQL VVMNRLKNNE ATRSAKSLGD 430 440 450 460 470 480 SIKKHIFHKS LMSRTPKRVP PSFHLASGSE TPNMSHVKPP KMRVLFQSPT PPTPTSSTIT 490 500 510 520 530 540 SVSLSTNTRH QLQKSISSAS LKIESSSSDS SSSCATSGSI SAPVSRQQSK ESPSGNGAAG 550 560 570 580 590 600 ASGQELDEID ADCCVTPLKI MSAVAKQLID KKSVAWDEHR LLEIEEYSNP STPVQQSTRY 610 620 630 640 650 660 KSEPNLSSIL PQVDAEEEDD GALTPIVEGR STMVASSSHM GRSITRKLMK GVSMGNLRFP 670 680 690 700 710 720 FSTPETTKRL VRSVSATLRR RPSGEESKPC PLAADAPLLE DVDDSDEDDD HHGAVDEDDD 730 740 750 760 770 780 DTLSENNGSS NELPAMSLGY QQILQSSVYR NMDLITSTPA LHLGRRSMSP ITKSTQRMPK 790 800 810 820 830 840 AMQESIMTPR SRKPVMLLTA LAGNGDKQLN LSFAEQDEPD SIGGTPTKQL EPPSLHSEDA 850 860 870 880 890 900 TSLGGYADIL GQHQSFALFN PRERTTSSSN SNEDSKPSNA LSSDFKEYLL TRSVLTASPA 910 920 930 940 950 960 DLSFASRSDD FGGASTTQDI DDLDESDLSP SLLYCLDGNE PTLASPFGNS NGRKRSAGTP 970 980 990 1000 LKSTLITNLD ADNKENMENL QEDHSRTKKL LITSPEKYPG ETAL

References

[1]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013599 Genomic DNA. Translation: AAF57827.2.
RefSeq	NP_611236.2.
UniGene	Dm.18592
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	A1ZAW3.
Genome annotation databases
Ensembl	FBgn0034249. Drosophila melanogaster. [Contig view]
GeneID	36996.
KEGG	dme:Dmel_CG6477.
NMPDR	fig|7227.3.peg.5993.
Organism-specific databases
FlyBase	FBgn0034249. RhoGAP54D.
Phylogenomic databases
OMA	A1ZAW3. TDIRAYF.
Family and domain databases
InterPro	IPR000198. RhoGAP. [Graphical view]
Gene3D	G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00324. RhoGAP. 1 hit. [Graphical view]
PROSITE	PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	801417.

Entry information

Entry name

A1ZAW3_DROME

Accession

Primary (citable) accession number: A1ZAW3

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)