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Protein
Submitted name:

p-element somatic inhibitor, isoform A

Gene

Psi

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • mRNA binding Source: FlyBase

GO - Biological processi

  • mRNA processing Source: FlyBase
  • negative regulation of mRNA splicing, via spliceosome Source: FlyBase
  • regulation of alternative mRNA splicing, via spliceosome Source: FlyBase
  • regulation of mRNA splicing, via spliceosome Source: FlyBase
  • regulation of transcription, DNA-templated Source: InterPro
  • spermatogenesis Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-450604. KSRP (KHSRP) binds and destabilizes mRNA.

Names & Taxonomyi

Protein namesi
Submitted name:
p-element somatic inhibitor, isoform AImported
Gene namesi
Name:PsiImported
ORF Names:CG8912Imported, Dmel_CG8912Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0014870. Psi.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: FlyBase

PTM / Processingi

Proteomic databases

PaxDbiA1ZAK9.
PRIDEiA1ZAK9.

Expressioni

Gene expression databases

BgeeiFBgn0014870.
ExpressionAtlasiA1ZAK9. differential.
GenevisibleiA1ZAK9. DM.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0086222.

Structurei

3D structure databases

ProteinModelPortaliA1ZAK9.
SMRiA1ZAK9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 107KHInterPro annotationAdd BLAST68
Domaini130 – 201KHInterPro annotationAdd BLAST72
Domaini234 – 305KHInterPro annotationAdd BLAST72
Domaini345 – 416KHInterPro annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG1676. Eukaryota.
ENOG410XZYE. LUCA.
OrthoDBiEOG091G08TR.

Family and domain databases

Gene3Di3.30.1370.10. 4 hits.
InterProiView protein in InterPro
IPR015096. FUBP_C.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
PfamiView protein in Pfam
PF09005. DUF1897. 2 hits.
PF00013. KH_1. 4 hits.
SMARTiView protein in SMART
SM00322. KH. 4 hits.
SUPFAMiSSF54791. SSF54791. 4 hits.

Sequencei

Sequence statusi: Complete.

A1ZAK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSGSGGGGG GGGGPGGASI TQAIAQAAAV AARLAASAGT SCEEQIRLPE
60 70 80 90 100
SVAGAFMGRS SNDTITHIQA ESGVKVQVMQ DQDRVIMLRG QRDTVTKGRE
110 120 130 140 150
MIQNMANRAG GGQVEVLLTI NMPPPGPSGY PPYQEIMIPG AKVGLVIGKG
160 170 180 190 200
GDTIKQLQEK TGAKMIIIQD GPNQELIKPL RISGEAQKIE HAKQMVLDLI
210 220 230 240 250
AQKDAQGQQQ GGRGGGGGGG GPGMGFNNFN NGNGGESTEV FVPKIAVGVV
260 270 280 290 300
IGKGGDMIRK IQTECGCKLQ FIQGKNDEMG DRRCVIQGTR QQVDDAKRTI
310 320 330 340 350
DGLIENVMQR NGMNRNGNGG GGGPGGDSGN SNYGYGYGVN HAQGGREEIT
360 370 380 390 400
FLVPASKCGI VIGRGGETIK LINQQSGAHT EMDRNASNPP NEKLFKSKGT
410 420 430 440 450
TDQVEAARQM ISEKINMELN VISRKPIGGG PGGGGGNSGG GQNNSHHNQQ
460 470 480 490 500
QGGYGGQNQM QGGDPNSGAG YQQQPWGGPY GQQGWDPSGQ QQQMAMANQG
510 520 530 540 550
GSAAGGASGG QDYSAQWIEY YKQMGCHREA EMIEQQMKAK QAGGSSGPVQ
560 570 580 590 600
QQQPQQQQQS QQQTGGAGAG GADYSAQWAE YYRSVGKIEE AEAIEKTLKN
610 620 630 640 650
KQNGSGGQSS TPNPSQGGSG QQQPNPAAAA AAAAAAAAAA GGYGQSMTPT
660 670 680 690 700
QYAQYSQYYA AAAAAGGQPQ GAPQPGGGQS GGPPGNYPGN YPGAGYGGYP
710
GAPGQQQQKS HKNDNH
Length:716
Mass (Da):73,448
Last modified:February 6, 2007 - v1
Checksum:i688C9FEE4E09360D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAM70893.2.
RefSeqiNP_725623.2. NM_166200.3.
UniGeneiDm.7661.

Genome annotation databases

EnsemblMetazoaiFBtr0087073; FBpp0086221; FBgn0014870.
GeneIDi36889.
UCSCiCG8912-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAM70893.2.
RefSeqiNP_725623.2. NM_166200.3.
UniGeneiDm.7661.

3D structure databases

ProteinModelPortaliA1ZAK9.
SMRiA1ZAK9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0086222.

Proteomic databases

PaxDbiA1ZAK9.
PRIDEiA1ZAK9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0087073; FBpp0086221; FBgn0014870.
GeneIDi36889.
UCSCiCG8912-RA. d. melanogaster.

Organism-specific databases

CTDi36889.
FlyBaseiFBgn0014870. Psi.

Phylogenomic databases

eggNOGiKOG1676. Eukaryota.
ENOG410XZYE. LUCA.
OrthoDBiEOG091G08TR.

Enzyme and pathway databases

ReactomeiR-DME-450604. KSRP (KHSRP) binds and destabilizes mRNA.

Miscellaneous databases

GenomeRNAii36889.

Gene expression databases

BgeeiFBgn0014870.
ExpressionAtlasiA1ZAK9. differential.
GenevisibleiA1ZAK9. DM.

Family and domain databases

Gene3Di3.30.1370.10. 4 hits.
InterProiView protein in InterPro
IPR015096. FUBP_C.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
PfamiView protein in Pfam
PF09005. DUF1897. 2 hits.
PF00013. KH_1. 4 hits.
SMARTiView protein in SMART
SM00322. KH. 4 hits.
SUPFAMiSSF54791. SSF54791. 4 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA1ZAK9_DROME
AccessioniPrimary (citable) accession number: A1ZAK9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 7, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.