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Protein
Submitted name:

Glutamate oxaloacetate transaminase 1, isoform B

Gene

Got1

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • aspartate biosynthetic process Source: GO_Central
  • glutamate biosynthetic process Source: FlyBase
  • imaginal disc-derived wing morphogenesis Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Enzyme and pathway databases

ReactomeiR-DME-70263. Gluconeogenesis.
R-DME-70614. Amino acid synthesis and interconversion (transamination).

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamate oxaloacetate transaminase 1, isoform BImported (EC:2.6.1.1Imported)
Gene namesi
Name:Got1Imported
ORF Names:CG8430Imported, Dmel_CG8430Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0001124. Got1.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: FlyBase
  • peroxisome Source: FlyBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA1ZAA5.
PRIDEiA1ZAA5.

Expressioni

Gene expression databases

BgeeiFBgn0001124.
ExpressionAtlasiA1ZAA5. baseline.
GenevisibleiA1ZAA5. DM.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiA1ZAA5. 1 interactor.
STRINGi7227.FBpp0086370.

Structurei

3D structure databases

ProteinModelPortaliA1ZAA5.
SMRiA1ZAA5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 418Aminotran_1_2InterPro annotationAdd BLAST369

Phylogenomic databases

eggNOGiKOG1411. Eukaryota.
COG1448. LUCA.
GeneTreeiENSGT00390000014081.
InParanoidiA1ZAA5.
OMAiMETFKQD.
OrthoDBiEOG091G06G3.
PhylomeDBiA1ZAA5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

A1ZAA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFIILKRLNY PGLLQNFQLS TMSIYADVPK GPAIEVFALT QAFKDDSNPN
60 70 80 90 100
KVNLSVGAYR TDAGVPWVLP VVRKTEISIA SDEQVNHEYL PVTGLETFTN
110 120 130 140 150
AATELVLGAD SPAIKENRAF GVQTISGTGA LRVAADFLHT QLNRNVVYYS
160 170 180 190 200
NPTWENHHKI FCDAGFTTVK SYRYWDQNKR ELDFKNMLAD LNDAPPGAVI
210 220 230 240 250
ILHACAHNPT GIDPTQEQWT ELADLMEKKK LFPLFDSAYQ GFASGDPDRD
260 270 280 290 300
AWAARYFVQR GFELFICQSF AKNFGLYCER TGNLAVVQKN GATKAAVHSQ
310 320 330 340 350
LTLLIRGQYS NPPAYGARIV SKVLNTPELR KEWMASIQAM SSRIREMRTA
360 370 380 390 400
LRDKLVALGT PGTWDHIVNQ IGMFSYTGLN ESHVRVLIDQ YHIYLLKTGR
410 420 430
ISMSGLNKGN VEYVAKAIHA AVTGSGESAS CPCENKL
Length:437
Mass (Da):48,579
Last modified:February 6, 2007 - v1
Checksum:i68B5E681AB060E9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAM70954.1.
RefSeqiNP_725534.1. NM_166148.2.
UniGeneiDm.3647.

Genome annotation databases

EnsemblMetazoaiFBtr0087231; FBpp0086370; FBgn0001124.
GeneIDi36782.
UCSCiCG8430-RB. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAM70954.1.
RefSeqiNP_725534.1. NM_166148.2.
UniGeneiDm.3647.

3D structure databases

ProteinModelPortaliA1ZAA5.
SMRiA1ZAA5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA1ZAA5. 1 interactor.
STRINGi7227.FBpp0086370.

Proteomic databases

PaxDbiA1ZAA5.
PRIDEiA1ZAA5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0087231; FBpp0086370; FBgn0001124.
GeneIDi36782.
UCSCiCG8430-RB. d. melanogaster.

Organism-specific databases

CTDi2805.
FlyBaseiFBgn0001124. Got1.

Phylogenomic databases

eggNOGiKOG1411. Eukaryota.
COG1448. LUCA.
GeneTreeiENSGT00390000014081.
InParanoidiA1ZAA5.
OMAiMETFKQD.
OrthoDBiEOG091G06G3.
PhylomeDBiA1ZAA5.

Enzyme and pathway databases

ReactomeiR-DME-70263. Gluconeogenesis.
R-DME-70614. Amino acid synthesis and interconversion (transamination).

Miscellaneous databases

GenomeRNAii36782.

Gene expression databases

BgeeiFBgn0001124.
ExpressionAtlasiA1ZAA5. baseline.
GenevisibleiA1ZAA5. DM.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA1ZAA5_DROME
AccessioniPrimary (citable) accession number: A1ZAA5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 30, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.