Unreviewed, UniProtKB/TrEMBL A1Z9N0 (A1Z9N0_DROME)

Names and origin

Protein names

Submitted name:
    Optic atrophy 1-like, isoform A EMBL AAF58275.2
    EC=3.6.1.-

Gene names

Name:	opa1-like FlyBase FBgn0086250
ORF Names:	Dmel_CG8479 EMBL AAF58275.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	972 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the dynamin family. RuleBase RU003932V0

Ontologies

Keywords
Ligand	GTP-binding RuleBase RU003932V0 Spearmint SPM001401 Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mitochondrial fusion Inferred from mutant phenotype. Source: FlyBase
Molecular function	GTP binding Inferred from electronic annotation. Source: InterPro GTPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1Z9N0-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: FD9E6C53320D2A03	FASTA	972	111,795
	10 20 30 40 50 60 MLRIYQNTYR RTARKAVVYS TKVACCNHST LCGITSHPRR AQDSGSSSSN GRHRGHEEFL 70 80 90 100 110 120 LAGNPARGWQ MPPPSRGYGM LVVRILRGAL KLRYIVLGGA IGGGVSLSKK YEEWKDGLPN 130 140 150 160 170 180 FKWLEDAMPQ GERWSQFSRN LIEVGSLVKN AIEVDPKLKQ LGEDKLSEWR NWFDSRLDDA 190 200 210 220 230 240 IEAADYQGVQ IVETKDDLKA KTTVAALGIT SDESRKKYEK LQSQVETLQT EIMNVQIKYQ 250 260 270 280 290 300 KELEKMEKEN RELRQQYLIL KTNKKTTAKK IKKSLIDMYS EVLDELSGYD TGYTMADHLP 310 320 330 340 350 360 RVVVVGDQSS GKTSVLESIA KARIFPRGSG EMMTRAPVKV TLAEGPYHVA QFRDSDREYD 370 380 390 400 410 420 LTKESDLQDL RRDVEFRMKA SVRGGKTVSN EVIAMTVKGP GLQRMVLVDL PGIISTMTVD 430 440 450 460 470 480 MASDTKDSIH QMTKHYMSNP NAIILCIQDG SVDAERSNVT DLVMQCDPLG RRTIFVLTKV 490 500 510 520 530 540 DLAEELADPD RIRKILSGKL FPMKALGYYA VVTGRGRKDD SIDAIRQYEE DFFKNSKLFH 550 560 570 580 590 600 RRGVIMPHQV TSRNLSLAVS DRFWKMVRET IEQQADAFKA TRFNLETEWK NNFPRLRESG 610 620 630 640 650 660 RDELFDKAKG EILDEVVTLS QISAKKWDDA LSTKLWEKLS NYVFESIYLP AAQSGSQNSF 670 680 690 700 710 720 NTMVDIKLRQ WAEQALPAKS VEAGWEALQQ EFISLMERSK KAQDHDGIFD QLKSAVVDEA 730 740 750 760 770 780 IRRHSWEDKA IDMLRVIQLN TLEDRFVHDK QEWDSAVKFL ESSVNAKLVQ TEETLAQMFG 790 800 810 820 830 840 PGQMRRITHW QYLTQDQQKR RSVKNELDKI LKNDTKHLPT LTHDELTTVR KNLQRDNVDV 850 860 870 880 890 900 DTDYIRQTWF PVYRKHFLQQ ALQRAKDCRK AYYLYTQQGA ECEISCSDVV LFWRIQQVIK 910 920 930 940 950 960 ITGNALRQQV INREARRLDK EIKAVLDEFS DDEEKKGYLL TGKRVLLAEE LIKVRQIQEK 970 LEEFINSLNQ EK

References

[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013599 Genomic DNA. Translation: AAF58275.2.
RefSeq	NP_725369.1.
UniGene	Dm.7707
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	A1Z9N0.
Genome annotation databases
Ensembl	FBgn0086250. Drosophila melanogaster. [Contig view]
GeneID	36578.
NMPDR	fig|7227.3.peg.5191.
Organism-specific databases
FlyBase	FBgn0086250. opa1-like.
Phylogenomic databases
OMA	A1Z9N0. KHSSGIK.
Family and domain databases
InterPro	IPR001401. Dynamin_GTPase. [Graphical view]
Pfam	PF00350. Dynamin_N. 1 hit. [Graphical view]
PRINTS	PR00195. DYNAMIN.
SMART	SM00053. DYNc. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	799304.

Entry information

Entry name

A1Z9N0_DROME

Accession

Primary (citable) accession number: A1Z9N0

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)