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Protein
Submitted name:

FI05376p

Gene

pea

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent RNA helicase activity Source: FlyBase
  • RNA binding Source: GO_Central

GO - Biological processi

  • chromatin organization Source: FlyBase
  • mRNA splicing, via spliceosome Source: FlyBase
  • oogenesis Source: FlyBase
  • regulation of alternative mRNA splicing, via spliceosome Source: FlyBase
  • spermatid development Source: FlyBase
  • ventral cord development Source: FlyBase

Keywordsi

Molecular functionHydrolaseSAAS annotationImported
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
FI05376pImported
Submitted name:
PeanutsImported (EC:3.6.1.3Imported)
Gene namesi
Name:peaImported
Synonyms:pea-RAImported
ORF Names:CG8241Imported, Dmel_CG8241Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0086895. pea.

Subcellular locationi

GO - Cellular componenti

  • catalytic step 2 spliceosome Source: FlyBase
  • cytoplasm Source: GO_Central
  • nucleus Source: FlyBase
  • precatalytic spliceosome Source: FlyBase
  • spliceosomal complex Source: FlyBase

Expressioni

Gene expression databases

BgeeiFBgn0086895.

Interactioni

Protein-protein interaction databases

IntActiA1Z9L3. 1 interactor.
STRINGi7227.FBpp0086647.

Structurei

3D structure databases

SMRiA1Z9L3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini285 – 356S1 motifInterPro annotationAdd BLAST72
Domaini596 – 759Helicase ATP-bindingInterPro annotationAdd BLAST164
Domaini777 – 957Helicase C-terminalInterPro annotationAdd BLAST181

Phylogenomic databases

eggNOGiENOG410INHE. Eukaryota.
KOG0922. Eukaryota.
KOG0925. Eukaryota.
COG1185. LUCA.
COG1643. LUCA.
GeneTreeiENSGT00880000137867.
KOiK12818.
OMAiIQKAICS.
OrthoDBiEOG091G030Q.

Family and domain databases

InterProiView protein in InterPro
IPR002464. DNA/RNA_helicase_DEAH_CS.
IPR011709. DUF1605.
IPR007502. Helicase-assoc_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR022967. S1_dom.
IPR003029. S1_domain.
PfamiView protein in Pfam
PF04408. HA2. 1 hit.
PF00271. Helicase_C. 1 hit.
PF07717. OB_NTP_bind. 1 hit.
PF00575. S1. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00847. HA2. 1 hit.
SM00490. HELICc. 1 hit.
SM00316. S1. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00690. DEAH_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS50126. S1. 1 hit.

Sequencei

Sequence statusi: Complete.

A1Z9L3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDELQKLEYL SLVSKICTEL DNHLGINDKD LAEFIIDLEN KNRTYDTFRK
60 70 80 90 100
ALLDNGAEFP DSLVQNLQRI INLMRPSRPG GASQEKTVGD KKEDKKSQLL
110 120 130 140 150
KMFPGLALPN DTYSKKEESD DDEKVKAKPE KHSETHKKTD MSDVDAAMME
160 170 180 190 200
LEALAPGEGA TLVRPHKEVS SRDRHKRRSR DRDTKRRSRS REDRHSDRRR
210 220 230 240 250
SRSRDKERRR RSRSRDNRRR SRSREDRDRD RDRRHKSSSS RDHHERRRRS
260 270 280 290 300
RSRSTERRDR RDRSRDCSEK MPPPSAAMTD DPEAGKIYSG KIANIVPFGC
310 320 330 340 350
FVQLFGLRKR WEGLVHISQL RAEGRVTDVT EVVTRNQTVK VKVMSITGQK
360 370 380 390 400
VSLSMKEVDQ DSGKDLNPLS HAPEDDESLR DRNPDGPFSS STSMLNLQGN
410 420 430 440 450
GMEGDEHESR KRVTRISSPE RWEIKQMISS GVLDRSEMPD FDEETGLLPK
460 470 480 490 500
DEDDEADIEI EIVEEEPPFL SGHGRALHDL SPVRIVKNPD GSLAQAAMMQ
510 520 530 540 550
SALSKERREQ KMLQREQEIE AMPTSLNKNW IDPLPEDESR SLAANMRGMA
560 570 580 590 600
AAPPEVPEWK KHVIGGKKSS FGKKTDLTLV EQRQSLPIYK LRDDLIKAVT
610 620 630 640 650
DNQILIVIGE TGSGKTTQIT QYLGECGFTA RGKIGCTQPR RVAAMSVAKR
660 670 680 690 700
VAEEYGCRLG QEVGYTIRFE DCTSPETIIK YMTDGMLLRE CLMEAELKSY
710 720 730 740 750
SVIMLDEAHE RTIHTDVLFG LLKTAVQKRP ELKLIVTSAT LDAVKFSQYF
760 770 780 790 800
FKAPIFTIPG RTFPVEVLYT KEPETDYLDA SLITVMQIHL REPPGDILLF
810 820 830 840 850
LTGQEEIDTA CEILYERMKS LGPDVPELII LPVYSALPSE MQTRIFDPAP
860 870 880 890 900
AGSRKVVIAT NIAETSLTID GIFYVVDPGF VKQKVYNSKT GMDSLVVTPI
910 920 930 940 950
SQAAAKQRAG RAGRTGPGKT YRLYTERAYR DEMLPTPVPE IQRTNLATTV
960 970 980 990 1000
LQLKTMGIND LLHFDFMDAP PVESLVMALE QLHSLSALDD EGLLTRLGRR
1010 1020 1030 1040 1050
MAEFPLEPNL SKMLIMSVAL QCSDEILTIV SMLSVQNVFY RPKDKQALAD
1060 1070 1080 1090 1100
QKKAKFNQAE GDHLTLLAVY NSWKNNKFSN AWCYENFVQI RTLKRSQDVR
1110 1120 1130 1140 1150
KQLLGIMDRH KLDVVSAGKN SVRIQKAICS GFFRNAAKKD PQEGYRTLVD
1160 1170 1180 1190 1200
SQVVYIHPSS ALFNRQPEWV IYHELVQTTK EYMREVTTID PKWLVEFAPS
1210 1220 1230 1240
FFRFSDPTKL SKFKKNQRLE PLYNKYEEPN AWRISRVRRR RN
Length:1,242
Mass (Da):141,936
Last modified:February 6, 2007 - v1
Checksum:i1F1B6160E8B4637C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58294.1.
BT044222 mRNA. Translation: ACH92287.1.
RefSeqiNP_610928.1. NM_137084.3.
UniGeneiDm.12451.

Genome annotation databases

EnsemblMetazoaiFBtr0087518; FBpp0086647; FBgn0086895.
GeneIDi36561.
KEGGidme:Dmel_CG8241.
UCSCiCG8241-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiA1Z9L3_DROME
AccessioniPrimary (citable) accession number: A1Z9L3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: August 30, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported