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Protein
Submitted name:

CG8545

Gene

CG8545-RA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei467S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei494S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei511S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei568NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, RNA-bindingPROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CG8545Imported
Submitted name:
LD11307pImported
Gene namesi
Name:CG8545-RAImported
ORF Names:CG8545Imported, Dmel_CG8545Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033741. CG8545.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiFBgn0033741.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0087045.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini351 – 638SAM_MT_RSMB_NOPInterPro annotationAdd BLAST288

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1122. Eukaryota.
COG0144. LUCA.
KOiK14835.
OMAiDVQRCYN.
OrthoDBiEOG091G0685.

Family and domain databases

InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR031341. Methyltr_RsmF_N.
IPR001678. MeTrfase_RsmB/NOP2.
IPR011023. Nop2p.
IPR023267. RCMT.
IPR023273. RCMT_NOP2.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF17125. Methyltr_RsmF_N. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
PR02012. RCMTNOP2.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00446. nop2p. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

A1Z909-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKAEYSEK PKKGPGRKAR KQGPPVFRKQ SFAPMEEEDK KLSHRQKQRF
60 70 80 90 100
VKREQKKVVQ KAKLQEKRAK GKLPQPAKRK TAYNSDSDPE DNEEEPQVAS
110 120 130 140 150
SDEEVPQLVP APKGQKATAP KGFTDDNDAW LKPKKQQKQP ETESEEEEEE
160 170 180 190 200
DEESEEDSED ELGEECEEEE EGDDEEGLES DDDTAQVGKL ADLSDDDDAN
210 220 230 240 250
SDDDFDISGE EDGAQADSDE EEDEDDDDDD DDDDDDKLPI ERANKKLKKR
260 270 280 290 300
EAEEAQLADD EMLETVDKQD VFQLPVEGEE TEKDLTLQEV QQRIKDVSLV
310 320 330 340 350
LSDFKRYRQA DRSRGEYIDL LRRDLCLYYS YNEFLMEKLM DMLPLTELME
360 370 380 390 400
YLEASEIARP LTIRTNTLKT RRRDLAGALI NRGVNLDPLG KWTKVGLVVF
410 420 430 440 450
NSQVPLGATP EYLAGHYMIQ GASSLLPVMA LAPQENERIL DMCSAPGGKG
460 470 480 490 500
SHIASIMKNT GVLFANDSNR DRIKAIVANF HRLGIVNAVV SCEDGTKFRN
510 520 530 540 550
IMTGFDRVLL DAPCTGTGVV SKDPSVKTTK SEVDVQRCYN LQRKLLLTAI
560 570 580 590 600
DCTDAKSSTG GYIVYSTCSV LPEENEWVID YALKKRNVKL VPTGLDFGVE
610 620 630 640 650
GFTKFRQHRF HPSLNLTKRY YPHTHNMDGF YVAKLKKFSN TIPITKEQQE
660 670 680 690 700
EDEKQLDEAI EADATTEAAA ESEEVEEEVA SKEKGPRKLL GKRAGKPSFT
710 720 730 740 750
EIEQELKKKK REESKTKYVA KVFEQPVKKP KPEKPAEKKN EKSQAPDKQT
760 770 780 790 800
NSSESPSKSA PKQKQTNGKT TVSNSDAKSF NKKNKGSQPK ENGAGSPAKP
810 820 830 840 850
DDNKPTTNGT NSPSKSAIKE TKTKPQPKGK QSPKGNAKLA KAPRVDIDDV
860 870 880 890
PILEGKPIKK QNKLKQKSKQ IGQLKKSTAG ANAGKKQKFK K
Length:891
Mass (Da):99,841
Last modified:February 6, 2007 - v1
Checksum:i679C9AB7B4E36CB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58504.2.
BT088930 mRNA. Translation: ACT56594.1.
RefSeqiNP_610786.2. NM_136942.3.
UniGeneiDm.2211.

Genome annotation databases

EnsemblMetazoaiFBtr0087934; FBpp0087045; FBgn0033741.
GeneIDi36365.
KEGGidme:Dmel_CG8545.
UCSCiCG8545-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiA1Z909_DROME
AccessioniPrimary (citable) accession number: A1Z909
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 22, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported