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Protein
Submitted name:

Sec24AB ortholog, isoform A

Gene

Sec24AB

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transportSAAS annotation, Transport

Enzyme and pathway databases

ReactomeiR-DME-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-DME-5694530. Cargo concentration in the ER.
R-DME-983170. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Names & Taxonomyi

Protein namesi
Submitted name:
Sec24AB ortholog, isoform AImported
Submitted name:
Sec24AB ortholog, isoform BImported
Gene namesi
Name:Sec24ABImported
Synonyms:sec24Imported
ORF Names:CG1472Imported, Dmel_CG1472Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033460. Sec24AB.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0033460.
ExpressionAtlasiA1Z813. baseline.

Interactioni

Protein-protein interaction databases

IntActiA1Z813. 3 interactors.
STRINGi7227.FBpp0087536.

Structurei

3D structure databases

ProteinModelPortaliA1Z813.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini509 – 545zf-Sec23_Sec24InterPro annotationAdd BLAST37
Domaini582 – 818Sec23_trunkInterPro annotationAdd BLAST237
Domaini824 – 908Sec23_BSInterPro annotationAdd BLAST85
Domaini919 – 1021Sec23_helicalInterPro annotationAdd BLAST103
Domaini1061 – 1130Gelsolin-likeInterPro annotationAdd BLAST70

Phylogenomic databases

eggNOGiKOG1985. Eukaryota.
COG5028. LUCA.
GeneTreeiENSGT00590000082962.
KOiK14007.
OMAiLTINAMP.
OrthoDBiEOG091G011M.
PhylomeDBiA1Z813.

Family and domain databases

Gene3Di3.40.20.10. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR029006. ADF-H/Gelsolin-like_dom.
IPR007123. Gelsolin-like_dom.
IPR006900. Sec23/24_helical_dom.
IPR006896. Sec23/24_trunk_dom.
IPR012990. Sec23_24_beta_S.
IPR002035. VWF_A.
IPR006895. Znf_Sec23_Sec24.
[Graphical view]
PfamiPF00626. Gelsolin. 1 hit.
PF08033. Sec23_BS. 1 hit.
PF04815. Sec23_helical. 1 hit.
PF04811. Sec23_trunk. 1 hit.
PF04810. zf-Sec23_Sec24. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF81811. SSF81811. 1 hit.
SSF82754. SSF82754. 1 hit.
SSF82919. SSF82919. 1 hit.

Sequencei

Sequence statusi: Complete.

A1Z813-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTYNPNFVP PAHAPMPLNG NNFVNGVQGS VQQQPGPPPG QQYIPQKQPQ
60 70 80 90 100
QFQQPPPAAA FPGAGAPGNV PPPQQFNSGI TNQFLPPTSG AATPLQQLPP
110 120 130 140 150
STLPPHLRPP AANGPPLTNG SNGASSANSS RTASPRPVGA APQYAQGPIA
160 170 180 190 200
AALNNPPLAS GLRPSPQPTH QSLANLTSNL ENLNLNTTRA NGGTSILPQP
210 220 230 240 250
QTQQQYAPTV TQKDGRGVAS AQTGPPQFND ANSLLAASGV AAALVPNAMA
260 270 280 290 300
TPFSGQKPPN LAPNPAKMFG SASMAGRPTP AGQRIPYGVP PPTNPEQQSQ
310 320 330 340 350
QNNNLQNAPP PPRVGAVWPP SLPNVAAPGA QPMMPPAQQT PQTYPYSQVY
360 370 380 390 400
QPGPQQQPPP PQSAVQPPPP GMFGTQPTGA PLQYQAQAPP QAYGQHPQQA
410 420 430 440 450
PQTAPGGPYG TTAPLNVAQQ GFSRLWGQDT IDLMQNRHIL TPATLPPPKV
460 470 480 490 500
VLHNQFHESI NCSPSIMRCT LTKIPESNSL LQKSRLPLGI VIHPFRDVNS
510 520 530 540 550
LPVIQCINIV RCRLCRTYIN PFVYFVDSKM WKCNLCYRVN ELPDDFQFDP
560 570 580 590 600
ATKTYGDVTR RPEVRSSTIE FIAPSEYMLR PPQPAMYLFL FDVSIIAQQS
610 620 630 640 650
GYLEAACAVL NRHLDEMPGD ARTQVGFICF DSFVHFYSMA EGLNQPHEMT
660 670 680 690 700
LLDIEDPFLP RPDSLLVNLK ECKELVRDLL KQLPKRFAHT HDPGSALGAA
710 720 730 740 750
LQVAFKLMQA SGGRITVFQS CLPNKGPGAL EPREDPNNRS AKDVAHLNPA
760 770 780 790 800
TDFYKRFALE CSGYQIACDL FLMNQQYSDM ATISGISKHS GGCVHHFPLY
810 820 830 840 850
QKTKPHMVES FRSCFKRYLT RKIGFEAVMR IRCTRGLQVH TFHGNFFVRS
860 870 880 890 900
TDLLSLPNVN PDAGYGMQIS YEESLTDAKT ICFQAALLYT NSEGERRIRV
910 920 930 940 950
HTVCLPVTAS LPEVMHSADT EAIIGLLSKM AVDRSVASNL SDARDAFINA
960 970 980 990 1000
TIDVYNAFKI AQNLPSGQSG QLIAPRSLAL LPLYILALLK HPAFRVGTST
1010 1020 1030 1040 1050
RLDDRVYAMD CMKTLPLDQL MKYVYPELYK IDALIYHARN SNISSNQDDD
1060 1070 1080 1090 1100
EDEDEPLPEL PRLQLSAEHL DSRSIFLMDC GTLIMIYVGL NVPPDVLEAV
1110 1120 1130 1140 1150
LGISSTAELG DYVYGLPNVV SNENDVLKRF ILRLNYDKPY SALVQIIRDT
1160 1170 1180
STAKGQFTER LTDDRSESSL SYYEFLQHIR AQVK
Length:1,184
Mass (Da):129,380
Last modified:February 6, 2007 - v1
Checksum:i046019ACB71736C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58880.1.
AE013599 Genomic DNA. Translation: AHN56055.1.
RefSeqiNP_001286257.1. NM_001299328.1.
NP_610531.1. NM_136687.5.

Genome annotation databases

EnsemblMetazoaiFBtr0088451; FBpp0087536; FBgn0033460.
FBtr0339406; FBpp0308496; FBgn0033460.
GeneIDi36025.
KEGGidme:Dmel_CG1472.
UCSCiCG1472-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58880.1.
AE013599 Genomic DNA. Translation: AHN56055.1.
RefSeqiNP_001286257.1. NM_001299328.1.
NP_610531.1. NM_136687.5.

3D structure databases

ProteinModelPortaliA1Z813.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA1Z813. 3 interactors.
STRINGi7227.FBpp0087536.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0088451; FBpp0087536; FBgn0033460.
FBtr0339406; FBpp0308496; FBgn0033460.
GeneIDi36025.
KEGGidme:Dmel_CG1472.
UCSCiCG1472-RA. d. melanogaster.

Organism-specific databases

CTDi36025.
FlyBaseiFBgn0033460. Sec24AB.

Phylogenomic databases

eggNOGiKOG1985. Eukaryota.
COG5028. LUCA.
GeneTreeiENSGT00590000082962.
KOiK14007.
OMAiLTINAMP.
OrthoDBiEOG091G011M.
PhylomeDBiA1Z813.

Enzyme and pathway databases

ReactomeiR-DME-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-DME-5694530. Cargo concentration in the ER.
R-DME-983170. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Miscellaneous databases

GenomeRNAii36025.

Gene expression databases

BgeeiFBgn0033460.
ExpressionAtlasiA1Z813. baseline.

Family and domain databases

Gene3Di3.40.20.10. 1 hit.
3.40.50.410. 1 hit.
InterProiIPR029006. ADF-H/Gelsolin-like_dom.
IPR007123. Gelsolin-like_dom.
IPR006900. Sec23/24_helical_dom.
IPR006896. Sec23/24_trunk_dom.
IPR012990. Sec23_24_beta_S.
IPR002035. VWF_A.
IPR006895. Znf_Sec23_Sec24.
[Graphical view]
PfamiPF00626. Gelsolin. 1 hit.
PF08033. Sec23_BS. 1 hit.
PF04815. Sec23_helical. 1 hit.
PF04811. Sec23_trunk. 1 hit.
PF04810. zf-Sec23_Sec24. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF81811. SSF81811. 1 hit.
SSF82754. SSF82754. 1 hit.
SSF82919. SSF82919. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA1Z813_DROME
AccessioniPrimary (citable) accession number: A1Z813
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 30, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.