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A1Z7M8

- A1Z7M8_DROME

UniProt

A1Z7M8 - A1Z7M8_DROME

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Protein
Submitted name:

Ance-4

Gene

Ance-4

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Note: Binds 1 zinc ion per subunit.UniRule annotation
  • Note: Binds 2 zinc ions per subunit.UniRule annotation

GO - Molecular functioni

  1. carboxypeptidase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ance-4Imported (EC:3.4.15.-Imported)
Gene namesi
Name:Ance-4Imported
ORF Names:CG8196Imported, Dmel_CG8196Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033366. Ance-4.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiA1Z7M8.
PRIDEiA1Z7M8.

Expressioni

Gene expression databases

BgeeiA1Z7M8.
ExpressionAtlasiA1Z7M8. differential.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0087745.

Structurei

3D structure databases

ProteinModelPortaliA1Z7M8.
SMRiA1Z7M8. Positions 20-606.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

eggNOGiNOG257068.
GeneTreeiENSGT00520000055576.
InParanoidiA1Z7M8.
KOiK01283.
OMAiGAIDFPY.
OrthoDBiEOG7CRTP8.
PhylomeDBiA1Z7M8.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

A1Z7M8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLLLLLVLI AGIGCATAAA NIDLEAKTFV NQSSDRYYRF YNEIAAETYS
60 70 80 90 100
ANNEEDFDAL FSKLNNVKRI AEELVSISRQ AATYDLDRIR SPQTKMALQE
110 120 130 140 150
LRTAGDLFVL GDDYFSSVQM NLAALQTLST DKDIEPYLGG ANMPNEDDSP
160 170 180 190 200
LAYFPDIQKI VQSSKDADEL KYYWEAWRDK NQLWASLNFY TIVQSYQRAA
210 220 230 240 250
KILEVPVHKL WYRYDSQEML QQMEQAMTEL RPAYQQLHAF VRQELHKKYG
260 270 280 290 300
SDVVNLNGPI PDHLFQQVLE QAWASGSILE DYYPRAQLPE FDEYVSHLTA
310 320 330 340 350
KTMVNESENF YTSLGFEPLS AEFHKNQLKE PNQDSPNDDC RPSIFDLTPH
360 370 380 390 400
VYLMYCEKVS FRKLMQYHSH MARVYYAQQK SHLPSYYFKA YNLEFAVGEA
410 420 430 440 450
VVLSASSPAH LTGRRLAKEV LSETALMSRL FRMAIHTILS IPLYYVHTKV
460 470 480 490 500
MHDLLNDTVD MDTVNKHYWR LMEQHAGIEA PSDRSEGAID FPYKFYVNID
510 520 530 540 550
QSFQTQKFIS EVLGYQFYRE FCKKSYNRGP LHNCDFYGSL AVGNDLKAMM
560 570 580 590 600
SLGSTKPWKQ VVGKILPNNT GLSSLALLEY YQPVLDWLNK YNKDANSKIG

WTASKKKIV
Length:609
Mass (Da):70,158
Last modified:February 6, 2007 - v1
Checksum:i7D5BEF404EEF840E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF59002.2.
RefSeqiNP_610442.2. NM_136598.3.

Genome annotation databases

EnsemblMetazoaiFBtr0088664; FBpp0087745; FBgn0033366.
GeneIDi35909.
KEGGidme:Dmel_CG8196.
UCSCiCG8196-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF59002.2 .
RefSeqi NP_610442.2. NM_136598.3.

3D structure databases

ProteinModelPortali A1Z7M8.
SMRi A1Z7M8. Positions 20-606.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7227.FBpp0087745.

Proteomic databases

PaxDbi A1Z7M8.
PRIDEi A1Z7M8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0088664 ; FBpp0087745 ; FBgn0033366 .
GeneIDi 35909.
KEGGi dme:Dmel_CG8196.
UCSCi CG8196-RA. d. melanogaster.

Organism-specific databases

CTDi 35909.
FlyBasei FBgn0033366. Ance-4.

Phylogenomic databases

eggNOGi NOG257068.
GeneTreei ENSGT00520000055576.
InParanoidi A1Z7M8.
KOi K01283.
OMAi GAIDFPY.
OrthoDBi EOG7CRTP8.
PhylomeDBi A1Z7M8.

Miscellaneous databases

GenomeRNAii 35909.
NextBioi 795771.

Gene expression databases

Bgeei A1Z7M8.
ExpressionAtlasi A1Z7M8. differential.

Family and domain databases

InterProi IPR001548. Peptidase_M2.
[Graphical view ]
PANTHERi PTHR10514. PTHR10514. 1 hit.
Pfami PF01401. Peptidase_M2. 1 hit.
[Graphical view ]
PRINTSi PR00791. PEPDIPTASEA.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  3. Cited for: GENOME REANNOTATION.
    Strain: BerkeleyImported.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  6. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  7. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.

Entry informationi

Entry nameiA1Z7M8_DROME
AccessioniPrimary (citable) accession number: A1Z7M8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 26, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3