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Protein

Angiotensin-converting enzyme

Gene

Ance-4

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Ance-4Imported
ORF Names:CG8196Imported, Dmel_CG8196Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033366 Ance-4

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500264189319 – 609Angiotensin-converting enzymeSequence analysisAdd BLAST591

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiA1Z7M8
PRIDEiA1Z7M8

Expressioni

Gene expression databases

BgeeiFBgn0033366
ExpressionAtlasiA1Z7M8 baseline and differential
GenevisibleiA1Z7M8 DM

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0087745

Structurei

3D structure databases

ProteinModelPortaliA1Z7M8
SMRiA1Z7M8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690 Eukaryota
ENOG410XPJ3 LUCA
InParanoidiA1Z7M8
OMAiGAKMPNE
OrthoDBiEOG091G0345
PhylomeDBiA1Z7M8

Family and domain databases

InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Complete.

A1Z7M8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLLLLVLI AGIGCATAAA NIDLEAKTFV NQSSDRYYRF YNEIAAETYS
60 70 80 90 100
ANNEEDFDAL FSKLNNVKRI AEELVSISRQ AATYDLDRIR SPQTKMALQE
110 120 130 140 150
LRTAGDLFVL GDDYFSSVQM NLAALQTLST DKDIEPYLGG ANMPNEDDSP
160 170 180 190 200
LAYFPDIQKI VQSSKDADEL KYYWEAWRDK NQLWASLNFY TIVQSYQRAA
210 220 230 240 250
KILEVPVHKL WYRYDSQEML QQMEQAMTEL RPAYQQLHAF VRQELHKKYG
260 270 280 290 300
SDVVNLNGPI PDHLFQQVLE QAWASGSILE DYYPRAQLPE FDEYVSHLTA
310 320 330 340 350
KTMVNESENF YTSLGFEPLS AEFHKNQLKE PNQDSPNDDC RPSIFDLTPH
360 370 380 390 400
VYLMYCEKVS FRKLMQYHSH MARVYYAQQK SHLPSYYFKA YNLEFAVGEA
410 420 430 440 450
VVLSASSPAH LTGRRLAKEV LSETALMSRL FRMAIHTILS IPLYYVHTKV
460 470 480 490 500
MHDLLNDTVD MDTVNKHYWR LMEQHAGIEA PSDRSEGAID FPYKFYVNID
510 520 530 540 550
QSFQTQKFIS EVLGYQFYRE FCKKSYNRGP LHNCDFYGSL AVGNDLKAMM
560 570 580 590 600
SLGSTKPWKQ VVGKILPNNT GLSSLALLEY YQPVLDWLNK YNKDANSKIG

WTASKKKIV
Length:609
Mass (Da):70,158
Last modified:February 6, 2007 - v1
Checksum:i7D5BEF404EEF840E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF59002.2
RefSeqiNP_610442.2, NM_136598.3

Genome annotation databases

EnsemblMetazoaiFBtr0088664; FBpp0087745; FBgn0033366
GeneIDi35909
UCSCiCG8196-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiA1Z7M8_DROME
AccessioniPrimary (citable) accession number: A1Z7M8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health