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Protein
Submitted name:

Sec31 ortholog, isoform A

Gene

Sec31

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • COPII-coated vesicle budding Source: FlyBase
  • defense response to Gram-negative bacterium Source: FlyBase
  • positive regulation of innate immune response Source: FlyBase
Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DME-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
SignaLinkiA1Z7J7.

Names & Taxonomyi

Protein namesi
Submitted name:
Sec31 ortholog, isoform AImported
Gene namesi
Name:Sec31Imported
Synonyms:sec31Imported
ORF Names:CG8266Imported, Dmel_CG8266Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033339. Sec31.

Subcellular locationi

GO - Cellular componenti

  • COPII vesicle coat Source: FlyBase
  • endoplasmic reticulum Source: FlyBase
  • endoplasmic reticulum exit site Source: FlyBase
  • ER to Golgi transport vesicle Source: FlyBase
  • Golgi membrane Source: GOC
  • Golgi stack Source: FlyBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA1Z7J7.
PRIDEiA1Z7J7.

Expressioni

Gene expression databases

BgeeiFBgn0033339.
GenevisibleiA1Z7J7. DM.

Interactioni

Protein-protein interaction databases

IntActiA1Z7J7. 5 interactors.
STRINGi7227.FBpp0087724.

Structurei

3D structure databases

ProteinModelPortaliA1Z7J7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 338WD_REPEATS_REGIONInterPro annotationAdd BLAST227

Phylogenomic databases

eggNOGiKOG0307. Eukaryota.
ENOG410XQ1D. LUCA.
GeneTreeiENSGT00390000003175.
OrthoDBiEOG091G01VB.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR024298. ACE1_Sec16_Sec31.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12931. Sec16_C. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1Z7J7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIKELQKTV NIAWSPAQQQ QILLAAGTAA QQFDSNANST LELYSPNFSD
60 70 80 90 100
ATYDLELRAS VSSQYKFQKL IWSPVGPHPS GLIVGGCEAG QINIYSADKL
110 120 130 140 150
LAGKEEPLLK RQDKHTGAVS GLDFNPFQNN LLASCASESE ILIWDLNNPE
160 170 180 190 200
TSMSPGTKTQ PLEDVKNVAW NRQVQHILAS VFSTRCVIWD LRKSQQIIKL
210 220 230 240 250
SDSQSRVRWH AIEWHPEAAT QVWLASEDDQ APVVQLWDLR YATAPAKTYQ
260 270 280 290 300
IHERGVLGMS WCLQDNDLMV SCGKDNRIYC WNPNTKIPEG EILSEVATTA
310 320 330 340 350
SWYSDVQFCP RNPALIASAS LEGAVSIYSL HGGTHHLVQT ANKIADSFPG
360 370 380 390 400
MDQFAQEPIP QQATQVVYHD LAHAPKWMKR PCGVAFGFGG KLVSFNGTSK
410 420 430 440 450
TVKVQQLTTE SALVDRANAL ERSLVDANYS DYCRQRADET PDQHGRYIWY
460 470 480 490 500
FIKANFELNP KEEMLNLLGY NKDDIDSKFN KFIKETDGNS HSDVDTLTTR
510 520 530 540 550
ISTLTHTQDN KFDGNAIDSQ NHNDFATPPR PQFKVPSGDH SDSLIAEAIL
560 570 580 590 600
TGNVDAAVEL CLEAQRIPEA LIIASTAGIE TLNRTQTRYL LQQKNELSHV
610 620 630 640 650
ISALVSRDWL DFVNRCTVDS WKEALVAALK HSERKVVDIC ERLGDRLLSE
660 670 680 690 700
CASSAEFTRN AMLCYICAGS IDKLVTAWYQ LKRLEQQNPG YKPNTTELQD
710 720 730 740 750
LAEMVMLMCK SLEQQGISVD LAGRFAGFLT EYGGLLASQG ALTAALQYIT
760 770 780 790 800
TLGGGAAASE SDVLQSLRDR INNAVNLDYT QPQAAVAAAP HGYQPTRGRG
810 820 830 840 850
SFSQPQPSAP MPYGQPPNQY AQPSWPAQVP PLQTSYPGAQ QPQAPPQIFN
860 870 880 890 900
PQPVKPEPLA QPPRPLSNAS SSGGPPPAGG ASSSGGSGLS GRSKYVLDPS
910 920 930 940 950
VAAPTSSYGM PYNPVPAPVP SAVPFGGGGV PGPAPQPASV PTYNSNAFNT
960 970 980 990 1000
NPIAAAQPYN PSPLMPAQQN QFVPGVNPIE TMPPPAVPPV IQNVQRNPTP
1010 1020 1030 1040 1050
PPGWNDPPAL KSSRAPKPKP VVEPSAAIFH PLFPVDPNQN QNGYVDPSQY
1060 1070 1080 1090 1100
QHAAPLGGVP NTYYNPAAFN NNPQQQQQHQ QSYLQPQQPA PGIQQPNWQG
1110 1120 1130 1140 1150
QQQTIGYTEQ PAPIQQQRQP APPKEKPPLP EEYIYLQTVL EELKNRCLGA
1160 1170 1180 1190 1200
TNDPRTKRKF VDVVKRLENL YDCLRDGKLT PTTVQYLNQI VQYIQISDYA
1210 1220 1230 1240
NAMEIHTQIA FGTDFAQCAG FMQGLKVLLQ SASELQLVLR
Length:1,240
Mass (Da):136,012
Last modified:February 6, 2007 - v1
Checksum:iC72782E3AC0525D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF59033.1.
RefSeqiNP_610414.1. NM_136570.4.

Genome annotation databases

EnsemblMetazoaiFBtr0088642; FBpp0087723; FBgn0033339.
GeneIDi35877.
UCSCiCG8266-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF59033.1.
RefSeqiNP_610414.1. NM_136570.4.

3D structure databases

ProteinModelPortaliA1Z7J7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA1Z7J7. 5 interactors.
STRINGi7227.FBpp0087724.

Proteomic databases

PaxDbiA1Z7J7.
PRIDEiA1Z7J7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0088642; FBpp0087723; FBgn0033339.
GeneIDi35877.
UCSCiCG8266-RA. d. melanogaster.

Organism-specific databases

CTDi35877.
FlyBaseiFBgn0033339. Sec31.

Phylogenomic databases

eggNOGiKOG0307. Eukaryota.
ENOG410XQ1D. LUCA.
GeneTreeiENSGT00390000003175.
OrthoDBiEOG091G01VB.

Enzyme and pathway databases

ReactomeiR-DME-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
SignaLinkiA1Z7J7.

Miscellaneous databases

GenomeRNAii35877.

Gene expression databases

BgeeiFBgn0033339.
GenevisibleiA1Z7J7. DM.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR024298. ACE1_Sec16_Sec31.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12931. Sec16_C. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS50082. WD_REPEATS_2. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA1Z7J7_DROME
AccessioniPrimary (citable) accession number: A1Z7J7
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 5, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.