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Protein
Submitted name:

BCR/ABL p210 fusion protein

Gene

BCR/ABL fusion

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
BCR/ABL p210 fusion proteinImported
Gene namesi
Name:BCR/ABL fusionImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiA1Z199.
PRIDEiA1Z199.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CTNNB1P352222EBI-7286259,EBI-491549

Protein-protein interaction databases

IntActiA1Z199. 1 interaction.
MINTiMINT-4508144.
STRINGi9606.ENSP00000361423.

Chemistry

BindingDBiA1Z199.

Structurei

3D structure databases

ProteinModelPortaliA1Z199.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini58 – 9740SH3InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0197. Eukaryota.
COG0515. LUCA.

Family and domain databases

InterProiIPR033221. ABL1.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR24418:SF88. PTHR24418:SF88. 1 hit.
PfamiPF00018. SH3_1. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

A1Z199-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QMLTNSCVKL QTVHSIPLTI NKEEALQRPV ASDFEPQGLS EAARWNSKEN
60 70 80 90
LLAGPSENDP NLFVALYDFV ASGDNTLSIT KGEKLRVLGY NHNGEWC
Length:97
Mass (Da):10,732
Last modified:February 6, 2007 - v1
Checksum:i38E9BE9266770D6B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei97 – 971Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF158045 mRNA. Translation: ABM21758.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF158045 mRNA. Translation: ABM21758.1.

3D structure databases

ProteinModelPortaliA1Z199.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA1Z199. 1 interaction.
MINTiMINT-4508144.
STRINGi9606.ENSP00000361423.

Chemistry

BindingDBiA1Z199.

Proteomic databases

PaxDbiA1Z199.
PRIDEiA1Z199.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0197. Eukaryota.
COG0515. LUCA.

Miscellaneous databases

ChiTaRSiABL1. human.
NextBioi35460636.

Family and domain databases

InterProiIPR033221. ABL1.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR24418:SF88. PTHR24418:SF88. 1 hit.
PfamiPF00018. SH3_1. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Detection of BCR/ABL, p210(b2-a2) Fusion Gene Protein with RT-PCR Based cDNA Sequencing in an African American Patient with Sickle Cell Anemia and Chronic Myelocytic Leukemia."
    Zhang H., Natarajan K., Kutlar F., Davis D.H., Nechtman J., Kutlar A.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Whole bloodImported.

Entry informationi

Entry nameiA1Z199_HUMAN
AccessioniPrimary (citable) accession number: A1Z199
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 11, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.