Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Homeobox protein Hox-B7

Gene

HOXB7

Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi137 – 196HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-B7
Gene namesi
Name:HOXB7
OrganismiGorilla gorilla gorilla (Western lowland gorilla)
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002854281 – 217Homeobox protein Hox-B7Add BLAST217

Expressioni

Gene expression databases

BgeeiENSGGOG00000002637.

Interactioni

Protein-protein interaction databases

STRINGi9593.ENSGGOP00000023202.

Structurei

3D structure databases

ProteinModelPortaliA1YFA5.
SMRiA1YFA5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi126 – 131Antp-type hexapeptide6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi210 – 217Glu-rich (acidic)8

Sequence similaritiesi

Belongs to the Antp homeobox family.Curated

Keywords - Domaini

Homeobox

Phylogenomic databases

GeneTreeiENSGT00900000140772.
HOVERGENiHBG016849.
InParanoidiA1YFA5.
KOiK09307.
OMAiCAPFEQN.

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like_sf.
IPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PRINTSiPR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A1YFA5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLYYANAL FSKYPASSSV FATGAFPEQT SCAFASNPQR QGYGAGSGAS
60 70 80 90 100
FAASMQGLYP GGGGMAGQSA AGVYAAGYGL EPSSFNMHCA PFEQNLSGVC
110 120 130 140 150
PGDSAKAAGA KEQRDSDLAA ESNFRIYPWM RSSGTDRKRG RQTYTRYQTL
160 170 180 190 200
ELEKEFHYNR YLTRRRRIEI AHALCLTERQ IKIWFQNRRM KWKKENKTAG
210
PGTTAQDRAE AEEEEEE
Length:217
Mass (Da):24,000
Last modified:February 6, 2007 - v1
Checksum:i47E543AB202FC354
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ976548 Genomic DNA. Translation: ABM46823.1.
RefSeqiXP_004041441.1. XM_004041393.2.

Genome annotation databases

EnsembliENSGGOT00000031742; ENSGGOP00000023202; ENSGGOG00000002637.
GeneIDi101124199.
KEGGiggo:101124199.

Similar proteinsi

Entry informationi

Entry nameiHXB7_GORGO
AccessioniPrimary (citable) accession number: A1YFA5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: February 6, 2007
Last modified: November 22, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families