A1WZK4 (CYSD_HALHL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	Hhal_2353

Organism

Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1)) [Complete proteome] [HAMAP]

Taxonomic identifier

349124 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Halorhodospira

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 304	304	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000008961

Sequences

	Sequence		Length	Mass (Da)
	A1WZK4 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 495DC67E73FE7B0F	FASTA	304	35,516
	10 20 30 40 50 60 MEISEARLTH LKELEAESIH IIREVAAEFD NPVMLYSIGK DSSVMLRLAL KAFYPGTPPF 70 80 90 100 110 120 PLMHVDTTWK FREMIAFRDR MARESGMELI VHINQEGVEQ GIGPFTHGSK VHTDVMKTQS 130 140 150 160 170 180 LKQAMDQHRF DAAFGGARRD EEKSRAKERV YSFRDRHHRW DPKGQRPELW QLYNGRVHKG 190 200 210 220 230 240 ESMRIFPLSN WTELDVWQYI YLEDIPIVPL YYAAERPVVD RDGTLIMVDD ERMPLEEGEQ 250 260 270 280 290 300 PRYEKVRFRT LGCYPLTGAI RSEADTLPEI IQEMLLTRTS ERQGRVIDHD SAGSMEEKKR QGYF

References

[1]

"Complete sequence of Halorhodospira halophila SL1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 244 / SL1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000544 Genomic DNA. Translation: ABM63116.1.
RefSeq	YP_001003918.1. NC_008789.1.
3D structure databases
ProteinModelPortal	A1WZK4.
SMR	A1WZK4. Positions 7-214.
ModBase	Search...
Protein-protein interaction databases
STRING	A1WZK4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4709236.
GenomeReviews	Gene locus Hhal_2353 in contig CP000544_GR.
KEGG	hha:Hhal_2353.
PATRIC	22099009. VBIHalHal112047_2329.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	RVIDHDA.
PhylomeDB	A1WZK4.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	HHAL349124:HHAL_2353-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_HALHL

Accession

Primary (citable) accession number: A1WZK4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program