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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei145 – 1451UniRule annotation
Active sitei551 – 5511UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciHHAL349124:GI3I-2344-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Hhal_2291Imported
OrganismiHalorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1))Imported
Taxonomic identifieri349124 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeHalorhodospira
ProteomesiUP000000647: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi349124.Hhal_2291.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1WZE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEHQDSDSA LREDIRDLGE LLGATLREQG GTELFETVER VRVLAKTARA
60 70 80 90 100
GDDQAAQELE RTLSELPPEQ VTPVARAFSQ FLNLANIAEQ HHRVRRSREW
110 120 130 140 150
ARTPEAQPLF GSLAETVPRL AADMEPEQLH EAICSMDINL VFTAHPTEVQ
160 170 180 190 200
RRTMLQKYNR IAGLLDNRDR FGQTPTEVAE TRLALKREIT AAWHSDEIRR
210 220 230 240 250
RRPTPQDEAR WGLAVVEQTL WDAVPRYLRS LDHTLREHTG RPLPLDCAPI
260 270 280 290 300
TFGSWMGGDR DGNPNVTHRV TRDVAILSRW MAAYLYERDI QRLVSTLSLQ
310 320 330 340 350
VCDDELRDEV GGEAWEPYRV VLKRLRARLR QTMRWAEAKL QGGRPPESDI
360 370 380 390 400
LTEVEDLRQP LLRCYYSLQR VGAGVVAEGE LLDTIRRVSC FGLTLMPMDI
410 420 430 440 450
RQHADRHTAA LDAITQAVGL GSYSEWDEET RQQWLFQELS HRRPLIPLDF
460 470 480 490 500
KPEREVQEVL DTIHMLEEIG PDAVGAYIVS HASKPSDILA VELLQKECGL
510 520 530 540 550
THPTRVVPLF ETRDTLARAA DTMEVLFKSD WYRQRIGGRQ EIMIGYSDST
560 570 580 590 600
KDAGHLTATW TLYQAQEQLV ALSRRQRVDL TLFHGRGGSI GRGGGPTHAA
610 620 630 640 650
ILAQPPGSVD GTLRVTEQGE VMQAKFGLPG IALRNLELYT TSVLEATVRP
660 670 680 690 700
PEPPPKRWRE ILERLSDRAM TAYRQTVKER PEFMDYFQAA TPIDEISRLT
710 720 730 740 750
IGSRPAKRAP DQMTVDSLRA IPWVFAWTQT RLMLPAWLGV GEALEEAIEE
760 770 780 790 800
GLTEELQEMF ARWPFFEAFL DMVEMVVAKA EPGVNRLYEH ALVPDELHSV
810 820 830 840 850
GDELRDRFAR TRDAVLTVTG HEEPLSDFPV VKRAVEVRNP YVDPLNLLQV
860 870 880
ELLRRSRMCE DDSLRRGLQV VINGIAAGMR NTG
Length:883
Mass (Da):100,294
Last modified:February 6, 2007 - v1
Checksum:i92399F06BB33971E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000544 Genomic DNA. Translation: ABM63054.1.
RefSeqiWP_011815076.1. NC_008789.1.
YP_001003856.1. NC_008789.1.

Genome annotation databases

EnsemblBacteriaiABM63054; ABM63054; Hhal_2291.
GeneIDi4709455.
KEGGihha:Hhal_2291.
PATRICi22098887. VBIHalHal112047_2268.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000544 Genomic DNA. Translation: ABM63054.1.
RefSeqiWP_011815076.1. NC_008789.1.
YP_001003856.1. NC_008789.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349124.Hhal_2291.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM63054; ABM63054; Hhal_2291.
GeneIDi4709455.
KEGGihha:Hhal_2291.
PATRICi22098887. VBIHalHal112047_2268.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciHHAL349124:GI3I-2344-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 244 / SL1Imported.

Entry informationi

Entry nameiA1WZE2_HALHL
AccessioniPrimary (citable) accession number: A1WZE2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: March 4, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.