A1WXX0 (GLMM_HALHL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Hhal_1768

Organism

Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1)) [Complete proteome] [HAMAP]

Taxonomic identifier

349124 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Halorhodospira

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 455	455	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000305641
Sites
	Active site	103	1	Phosphoserine intermediate By similarity
	Metal binding	103	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	103	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1WXX0 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 20DD2DFE20B0D7A8	FASTA	455	48,705
	10 20 30 40 50 60 MAEERSYFGT DGIRGRVGEA PITPDFVLRL GWAAGRVLAG EGQRKVVIGK DTRLSGYMFE 70 80 90 100 110 120 SALEAGFAAA GVHSLMLGPM PTPAIAYLTR TLHARAGVVI SASHNPHHDN GIKFFGPDGY 130 140 150 160 170 180 KLDDATEEAI ERLLQDGPPQ MVRCEELGRA TRINDAVGRY IEFCKGSVQR QIDLRGLRVV 190 200 210 220 230 240 VDCAHGATYQ AAPAVLAELG ADVVVIGNEP DGLNINVDHG SQHPERLCQR VVEASADVGV 250 260 270 280 290 300 AFDGDGDRVI MVDRYGRVID GDGLLYIIAT ARVARGQVRG AVVGTQMTNL GLEVALQELG 310 320 330 340 350 360 LVLERTRVGD RYVLERLLQV GGTLGGESSG HIICLDRTTT GDGLISALQV LEAMVTTGRP 370 380 390 400 410 420 LDELVAGMHY YPQRLVNVPV SRGPDVIRLP AVTEAVEEAE HQLGDHGRVL LRPSGTEPLL 430 440 450 RVMVEGADEG QVNRLADWLA VTVETAARGA ATDPI

References

[1]

"Complete sequence of Halorhodospira halophila SL1." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 244 / SL1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000544 Genomic DNA. Translation: ABM62532.1.
RefSeq	YP_001003334.1. NC_008789.1.
3D structure databases
ProteinModelPortal	A1WXX0.
ModBase	Search...
Protein-protein interaction databases
STRING	A1WXX0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4711021.
GenomeReviews	Gene locus Hhal_1768 in contig CP000544_GR.
KEGG	hha:Hhal_1768.
PATRIC	22097819. VBIHalHal112047_1740.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	AKEVPRY.
PhylomeDB	A1WXX0.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	HHAL349124:HHAL_1768-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_HALHL

Accession

Primary (citable) accession number: A1WXX0

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	February 6, 2007
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program