Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Gene

gpsA

Organism
Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H.UniRule annotation

Pathwayi: glycerophospholipid metabolism

This protein is involved in the pathway glycerophospholipid metabolism, which is part of Membrane lipid metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycerophospholipid metabolism and in Membrane lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei105NAD; via amide nitrogenUniRule annotation1
Binding sitei105SubstrateUniRule annotation1
Binding sitei138NAD; via amide nitrogenUniRule annotation1
Active sitei189Proton acceptorUniRule annotation1
Binding sitei253NADUniRule annotation1
Binding sitei279NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 14NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism
LigandNAD

Enzyme and pathway databases

UniPathwayiUPA00940

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(P)+]UniRule annotation (EC:1.1.1.94UniRule annotation)
Alternative name(s):
NAD(P)H-dependent glycerol-3-phosphate dehydrogenaseUniRule annotation
Gene namesi
Name:gpsAUniRule annotation
Ordered Locus Names:Hhal_1214
OrganismiHalorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1))
Taxonomic identifieri349124 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeHalorhodospira
Proteomesi
  • UP000000647 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000607851 – 332Glycerol-3-phosphate dehydrogenase [NAD(P)+]Add BLAST332

Proteomic databases

PRIDEiA1WWC7

Interactioni

Protein-protein interaction databases

STRINGi349124.Hhal_1214

Structurei

3D structure databases

ProteinModelPortaliA1WWC7
SMRiA1WWC7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni253 – 254Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSF Bacteria
COG0240 LUCA
HOGENOMiHOG000246853
KOiK00057
OMAiWLCKGFE
OrthoDBiPOG091H060E

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00394 NAD_Glyc3P_dehydrog, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

A1WWC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTIAVLGA GAWGTALASV LGRNGHAVRL WTREAEHAAA INAERVNQRH
60 70 80 90 100
LPDCPLPDSL TATADLETAL GGTDWLLIAV PSSAFRGLIE RLAPYRPGKV
110 120 130 140 150
VWATKGLESE SGGFLHDVVQ AGLDPAPAMA VISGPSFAAE VGQGLPTAIT
160 170 180 190 200
VAADDADLAA EVVRAFHNDR FRPYSSTDMT GVELGGAVKN VLAVATGASD
210 220 230 240 250
GLGLGANARA ALVTRGLAEI SRLGAALGAD PQTLIGLAGM GDLLLTCTDD
260 270 280 290 300
QSRNRRFGFA LGQGATVETA LASVGSTVEG ARTAAELHSL AERHSVEMPI
310 320 330
CNMVYRVVSG DTPLEQAVRE LMERTPKAEF DD
Length:332
Mass (Da):34,370
Last modified:February 6, 2007 - v1
Checksum:i5C60AC733F417B0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000544 Genomic DNA Translation: ABM61989.1
RefSeqiWP_011814012.1, NC_008789.1

Genome annotation databases

EnsemblBacteriaiABM61989; ABM61989; Hhal_1214
KEGGihha:Hhal_1214

Similar proteinsi

Entry informationi

Entry nameiGPDA_HALHL
AccessioniPrimary (citable) accession number: A1WWC7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 6, 2007
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health