Skip Header

Contribute Send feedback
Read comments (?) or add your own

A1WVP7 (A1WVP7_HALHL) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Hhal_0983
OrganismHalorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1)) [Complete proteome] [HAMAP] EMBL ABM61759.1
Taxonomic identifier349124 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Ectothiorhodospiraceae › Halorhodospira

Protein attributes

Sequence length624 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS001017

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS001017

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS001017

Subunit structure

Homodimer By similarity. HAMAP MF_00315

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
A1WVP7 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 42421FEE7B229C56

FASTA62467,051
        10         20         30         40         50         60 
MTMGTHDEDK VLLSAIDDPE DLRRLPLERL PAVAQEMRDY LVESVSQSGG HLAAGLGAVE 

        70         80         90        100        110        120 
LTLALHYALD TPRDRLVWDV GHQCYAHKVL TGRRSQLPRI RQAGGPAGFP VRDESPYDAF 

       130        140        150        160        170        180 
GVGHSSTSIS AALGMALAER AGGEHRRCAA IIGDGGLSAG EALEALNHAG DVKADLLVVL 

       190        200        210        220        230        240 
NDNEMSISEN VGALSNYLTR LLSEPLAGQL RRGARDMLRY LPPIHELARR TEGHVKGLLA 

       250        260        270        280        290        300 
PATLFEELGF HYFGPVDGHN VEGLVRVLRN LRDQPGPRLL HVVTRKGKGY APAEEDPISY 

       310        320        330        340        350        360 
HGVSCFDPAR GLTKGTPAKL NYTDVFSRWI CRAACTDERV VAITPAMREG SGLVEYARRF 

       370        380        390        400        410        420 
PERFFDVGIA EQHAVTLAAG LACEGARPVV AIYSTFLQRG YDQVIHDVAL QRLPVLFAVD 

       430        440        450        460        470        480 
RAGIVGADGA THQGTYDLSY LRCIPDLTVM APADEAECWR MLATGLVLEG ASAVRYPRGT 

       490        500        510        520        530        540 
GPGEALPDDM EPLPVGQAEV RREGGSGVAL LAFGALLPVA EAVGEELDAT VVNMRFVKPL 

       550        560        570        580        590        600 
DEALLRRLAG ECRHLVTLEE NVIAGGAGSG VAEYLSSIGV HTPITHLGLP DAPVHHGARN 

       610        620 
DILAEHGLDR DGVRRTVQGL LQQS

« Hide

References

[1]"Complete sequence of Halorhodospira halophila SL1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 244 / SL1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000544 Genomic DNA. Translation: ABM61759.1.
RefSeqYP_001002561.1. NC_008789.1.

3D structure databases

ProteinModelPortalA1WVP7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1WVP7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4709539.
GenomeReviewsGene locus Hhal_0983 in contig CP000544_GR.
KEGGhha:Hhal_0983.
PATRIC22096267. VBIHalHal112047_0977.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1154.
HOGENOMHBG571647.
OMALHPTGLA.
PhylomeDBA1WVP7.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR001017. DH_E1.
IPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1WVP7_HALHL
AccessionPrimary (citable) accession number: A1WVP7
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info