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A1WVN0 (UBIC_HALHL) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable chorismate--pyruvate lyase

Short name=CL
Short name=CPL
EC=4.1.3.40
Gene names
Name:ubiC
Ordered Locus Names:Hhal_0966
OrganismHalorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira halophila (strain DSM 244 / SL1)) [Complete proteome] [HAMAP]
Taxonomic identifier349124 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaChromatialesEctothiorhodospiraceaeHalorhodospira

Protein attributes

Sequence length187 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632

Catalytic activity

Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632

Subcellular location

Cytoplasm By similarity HAMAP MF_01632.

Sequence similarities

Belongs to the ubiC family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCytoplasm
   LigandPyruvate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchorismate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 187187Probable chorismate--pyruvate lyase HAMAP MF_01632
PRO_0000292067

Sites

Binding site801Substrate By similarity
Binding site1171Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
A1WVN0 [UniParc].

Last modified June 26, 2007. Version 2.
Checksum: 4C5ADCC4D9B3C55B

FASTA18720,591
        10         20         30         40         50         60 
MREHAAWQPQ AAAWRPGVAV VPGRPAPAVQ RLLTERGSLT ARLERLGPVR VHVLREAWQR 

        70         80         90        100        110        120 
PAPDEGVALE LPVGRHAWLR EVVLDCEGGP TIYARSIVPD RLLGPLARLP RLGERPLGRL 

       130        140        150        160        170        180 
LFSAADVQRG PLAVARLRGR EPLVRWLRGH GLPSPAGGWA RRSTLSVAGR RLLVTEVFFP 


EGVEGER 

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References

[1]"Complete sequence of Halorhodospira halophila SL1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 244 / SL1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000544 Genomic DNA. Translation: ABM61742.1.
RefSeqYP_001002544.1. NC_008789.1.

3D structure databases

ProteinModelPortalA1WVN0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1WVN0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4709467.
GenomeReviewsGene locus Hhal_0966 in contig CP000544_GR.
KEGGhha:Hhal_0966.
PATRIC22096233. VBIHalHal112047_0960.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG120169.
HOGENOMHBG644467.
ProtClustDBCLSK727637.

Enzyme and pathway databases

BioCycHHAL349124:HHAL_0966-MONOMER.

Family and domain databases

HAMAPMF_01632. UbiC.
[Tree]
InterProIPR007440. Chorismate--pyruvate_lyase.
[Graphical view]
KOK03181.
PfamPF04345. Chor_lyase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIC_HALHL
AccessionPrimary (citable) accession number: A1WVN0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 26, 2007
Last modified: January 25, 2012
This is version 26 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families