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A1WJL0 (PNCB_VEREI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Veis_2067
OrganismVerminephrobacter eiseniae (strain EF01-2) [Complete proteome] [HAMAP]
Taxonomic identifier391735 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeVerminephrobacter

Protein attributes

Sequence length406 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 406406Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000129491

Sequences

Sequence LengthMass (Da)Tools
A1WJL0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 66EF60BC4B47A6FD

FASTA40645,998
        10         20         30         40         50         60 
MIITSLLDTD LYKFTMMQVV LHQFPGAQVE YRFKCRNPGV QLAPYVAEIR GEIRSLCSLQ 

        70         80         90        100        110        120 
FQDAELDYLR SMRFIKSDFV DFLGLFRLNE KYISVAPRPG GEIDICIRGP WLHTILFEIP 

       130        140        150        160        170        180 
VLAIVNEVYF RNTQKVPDFP EGRRRLDAKI ALLQAEGLEE LKIADYGTRR RFSRAWHEEV 

       190        200        210        220        230        240 
LRVLVARLGT GDQCAEAPAG PGQFAGTSNV LYAMKLGVTP LGTMAHEYLQ ACQALGPRLR 

       250        260        270        280        290        300 
DSQVFGFEIW AREYRGDLGI ALSDVYGMSA FLRDFDLYFC KLFDGARQDS GDPFAWGERL 

       310        320        330        340        350        360 
LAHYRKLRVD PQSKTLIFSD ALTVTRTIEL YRQFRGRCQL AFGIGTHLTN DLGSPPAHEP 

       370        380        390        400 
LQVVIKMTRC NGQPVAKLAD SPGKGMCDDE KYLAYLRQVF DIPAQA 

« Hide

References

[1]"Complete sequence of chromosome 1 of Verminephrobacter eiseniae EF01-2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EF01-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000542 Genomic DNA. Translation: ABM57817.1.
RefSeqYP_996835.1. NC_008786.1.

3D structure databases

ProteinModelPortalA1WJL0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING391735.Veis_2067.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM57817; ABM57817; Veis_2067.
GeneID4692290.
KEGGvei:Veis_2067.
PATRIC24017791. VBIVerEis120356_2289.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMASIVCKVI.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycVEIS391735:GHY5-2088-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_VEREI
AccessionPrimary (citable) accession number: A1WJL0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 6, 2007
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways