Skip Header

Contribute Send feedback
Read comments (?) or add your own

A1WI76 (A1WI76_VEREI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Veis_1574
OrganismVerminephrobacter eiseniae (strain EF01-2) [Complete proteome] [HAMAP]
Taxonomic identifier391735 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Verminephrobacter

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2381Iron By similarity HAMAP MF_00323
Metal binding3191Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A1WI76 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 75613626500DE691

FASTA39844,169
        10         20         30         40         50         60 
MVRPEYPTRR ALGRRAGLRG AFATIAPMFS PFAPEPPYTH GQAERTAVLL CNLGTPDAPT 

        70         80         90        100        110        120 
APAVRRYLAQ FLSDRRVVEI PKLLWLPLLH GLILRTRPAR SAAQYASIWS AAGSPLALWT 

       130        140        150        160        170        180 
ARQAGLLRDD LDAAGHRVLV RHAMRYGNPS IASQLDALKA EGATRILILP LYPQYSATTT 

       190        200        210        220        230        240 
ASVFDAVYRW AARIRRLPEL RFVNRYHDHP DYIAALAHSV QTHWQQHGRP EQLVLSFHGL 

       250        260        270        280        290        300 
PERSRQLGDP YHCEVRKTAR LLAERLGLGQ ERYRVSFQSR FGNARWLQPY TRPTVEALGQ 

       310        320        330        340        350        360 
AGLRRVDLVC PGFTSDCRET LEEIDIEVRA AFLQAGGKEF HYIRCLNDSP QWITALACVA 

       370        380        390 
RQHLAGWPTQ PAAAAALAEA RNHALAGGAP AGSRATGP

« Hide

References

[1]"Complete sequence of chromosome 1 of Verminephrobacter eiseniae EF01-2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EF01-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000542 Genomic DNA. Translation: ABM57333.1.
RefSeqYP_996351.1. NC_008786.1.

3D structure databases

ProteinModelPortalA1WI76.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1WI76.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4690769.
GenomeReviewsGene locus Veis_1574 in contig CP000542_GR.
KEGGvei:Veis_1574.
NMPDRfig|391735.5.peg.1486.
PATRIC24016691. VBIVerEis120356_1744.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBA1WI76.

Enzyme and pathway databases

BioCycVEIS391735:VEIS_1574-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1WI76_VEREI
AccessionPrimary (citable) accession number: A1WI76
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info