Reviewed, UniProtKB/Swiss-Prot A1WD35 (PGK_ACISJ)

Names and origin

Protein names

Recommended name:
    Phosphoglycerate kinase
    EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Ajs_4056

Organism

Acidovorax sp. (strain JS42) [Complete proteome] [HAMAP]

Taxonomic identifier

232721 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000009602
Regions
	Nucleotide binding	350 – 353	4	ATP By similarity
	Region	25 – 27	3	Substrate binding By similarity
	Region	64 – 67	4	Substrate binding By similarity
Sites
	Binding site	41	1	Substrate By similarity
	Binding site	118	1	Substrate By similarity
	Binding site	151	1	Substrate By similarity
	Binding site	202	1	ATP By similarity
	Binding site	324	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1WD35-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 8FE8CBD757D5ED45	FASTA	397	41,179
	10 20 30 40 50 60 MHILRFSDLC AQGQARGQRV FIRADLNVPQ DDAGRITEDT RIRASVPCIQ MALEAGAAVM 70 80 90 100 110 120 VTSHLGRPTE GEFKPEDSLA PVAQRLSELL GREVPLVADW VDGVQVQPGQ VVLLENCRVN 130 140 150 160 170 180 KGEKKNDPEL AKKMAQLCDI YVNDAFGTAH RAEGTTYGIA EYAKVACAGP LLAAEIDAIQ 190 200 210 220 230 240 TALAHPKRPL VAIVAGSKVS TKLTILQSLS KNVDGLVVGG GIANTFMLAA GLPIGKSLAE 250 260 270 280 290 300 PDLVNEAKAV IAAMAARGAE VPIPTDVVVA KAFAADAPAT VKKASEVAED DLILDIGPET 310 320 330 340 350 360 AAQLAAQLKA AGTIVWNGPV GVFEFDQFAG GTKAIAQAIA ESSAFSIAGG GDTLAAIAKY 370 380 390 GIEKDVGYIS TGGGAFLEVL EGKTLPAIEI LQKRAAG

References

[1]

"Complete sequence of chromosome 1 of Acidovorax sp. JS42." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000539 Genomic DNA. Translation: ABM44160.1.
RefSeq	YP_988236.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1WD35.
Genome annotation databases
GeneID	4673443.
GenomeReviews	Gene locus Ajs_4056 in contig CP000539_GR.
KEGG	ajs:Ajs_4056.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	CGPESIK.
Family and domain databases
HAMAP	MF_00145. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PRINTS	PR00477. PHGLYCKINASE.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_ACISJ

Accession

Primary (citable) accession number: A1WD35

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)