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A1WD35

- PGK_ACISJ

UniProt

A1WD35 - PGK_ACISJ

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Acidovorax sp. (strain JS42)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei41 – 411SubstrateUniRule annotation
    Binding sitei118 – 1181SubstrateUniRule annotation
    Binding sitei151 – 1511SubstrateUniRule annotation
    Binding sitei202 – 2021ATPUniRule annotation
    Binding sitei324 – 3241ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi350 – 3534ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciASP232721:GHWE-4120-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:Ajs_4056
    OrganismiAcidovorax sp. (strain JS42)
    Taxonomic identifieri232721 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
    ProteomesiUP000000645: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 397397Phosphoglycerate kinasePRO_1000009602Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi232721.Ajs_4056.

    Structurei

    3D structure databases

    ProteinModelPortaliA1WD35.
    SMRiA1WD35. Positions 17-395.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni25 – 273Substrate bindingUniRule annotation
    Regioni64 – 674Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiFNVPLRE.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1WD35-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHILRFSDLC AQGQARGQRV FIRADLNVPQ DDAGRITEDT RIRASVPCIQ    50
    MALEAGAAVM VTSHLGRPTE GEFKPEDSLA PVAQRLSELL GREVPLVADW 100
    VDGVQVQPGQ VVLLENCRVN KGEKKNDPEL AKKMAQLCDI YVNDAFGTAH 150
    RAEGTTYGIA EYAKVACAGP LLAAEIDAIQ TALAHPKRPL VAIVAGSKVS 200
    TKLTILQSLS KNVDGLVVGG GIANTFMLAA GLPIGKSLAE PDLVNEAKAV 250
    IAAMAARGAE VPIPTDVVVA KAFAADAPAT VKKASEVAED DLILDIGPET 300
    AAQLAAQLKA AGTIVWNGPV GVFEFDQFAG GTKAIAQAIA ESSAFSIAGG 350
    GDTLAAIAKY GIEKDVGYIS TGGGAFLEVL EGKTLPAIEI LQKRAAG 397
    Length:397
    Mass (Da):41,179
    Last modified:February 6, 2007 - v1
    Checksum:i8FE8CBD757D5ED45
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000539 Genomic DNA. Translation: ABM44160.1.
    RefSeqiWP_011807137.1. NC_008782.1.
    YP_988236.1. NC_008782.1.

    Genome annotation databases

    EnsemblBacteriaiABM44160; ABM44160; Ajs_4056.
    GeneIDi4673443.
    KEGGiajs:Ajs_4056.
    PATRICi20693561. VBIAciSp27161_4280.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000539 Genomic DNA. Translation: ABM44160.1 .
    RefSeqi WP_011807137.1. NC_008782.1.
    YP_988236.1. NC_008782.1.

    3D structure databases

    ProteinModelPortali A1WD35.
    SMRi A1WD35. Positions 17-395.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 232721.Ajs_4056.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABM44160 ; ABM44160 ; Ajs_4056 .
    GeneIDi 4673443.
    KEGGi ajs:Ajs_4056.
    PATRICi 20693561. VBIAciSp27161_4280.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi FNVPLRE.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci ASP232721:GHWE-4120-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Acidovorax sp. JS42."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
      , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JS42.

    Entry informationi

    Entry nameiPGK_ACISJ
    AccessioniPrimary (citable) accession number: A1WD35
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3