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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Acidovorax sp. (strain JS42)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Ajs_3665Imported
OrganismiAcidovorax sp. (strain JS42)Imported
Taxonomic identifieri232721 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000000645 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi232721.Ajs_3665

Structurei

3D structure databases

ProteinModelPortaliA1WC01
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 205TubulinInterPro annotationAdd BLAST190
Domaini207 – 326Tubulin_CInterPro annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili151 – 171Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1WC01-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTIEMIESEE FNQGTQIKVI GVGGGGGNAV EHMISRNVQG VEFVTANTDA
60 70 80 90 100
QALTRSTAHR TIQLGASGLG AGSKPDKGRE AAEAAQEDIR QAIQGSHMLF
110 120 130 140 150
ITAGMGGGTG TGAAPVIARV AKEMGILTVG VVTKPFDWEG GRRMKNADDG
160 170 180 190 200
LAELEANVDS LIVVLNEKLL EVLGDDITQE EAFAHANDVL KNAVGGIAEI
210 220 230 240 250
INEYGQVNVD FEDVRTVMGE PGKAMMGTAT ASGPDRARIA AEQAIACPLL
260 270 280 290 300
EGIDLSGAKG VLVLVTASKG SLKLAESRLA MNTINAYASP DAHVIFGAAY
310 320 330 340 350
DDTLGDEIRV TVVATGLSRQ NARRQPMQVV QGSLRTGTDN VAYQMPMAGA
360 370 380 390 400
AVGVSAGMVG GAAQADYGSM AVPSVWRTNR SVATARVDAL SSGGMDELEI

PAFLRKQAD
Length:409
Mass (Da):42,439
Last modified:February 6, 2007 - v1
Checksum:i6235BCFBD17F4E6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000539 Genomic DNA Translation: ABM43776.1
RefSeqiWP_011806759.1, NC_008782.1

Genome annotation databases

EnsemblBacteriaiABM43776; ABM43776; Ajs_3665
KEGGiajs:Ajs_3665

Similar proteinsi

Entry informationi

Entry nameiA1WC01_ACISJ
AccessioniPrimary (citable) accession number: A1WC01
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health