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Reviewed, UniProtKB/Swiss-Prot A1WBQ7 (PYRB_ACISJ)

Last modified February 9, 2010. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Aspartate carbamoyltransferase
    EC=2.1.3.2
Alternative name(s):
    Aspartate transcarbamylase
      Short name=ATCase
Gene names
Name: pyrB
Ordered Locus Names: Ajs_3570
OrganismAcidovorax sp. (strain JS42) [Complete proteome] [HAMAP]
Taxonomic identifier232721 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax

Protein attributes

Sequence length320 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP MF_00001

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP MF_00001

Sequence similarities

Belongs to the ATCase/OTCase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 320320Aspartate carbamoyltransferase HAMAP MF_00001
PRO_0000321063

Sequences

Sequence LengthMass (Da)Tools
A1WBQ7-1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 9CEDFC008952A94C

FASTA32035,007
        10         20         30         40         50         60 
MLYKRNPQLN KNGELIHLLS IEGLPKDIVT HILDTATNFV SVQEREVKKV PLLRGKSVFN 

        70         80         90        100        110        120 
LFFENSTRTR TTFEIAAKRL SADVFNLDIA RSSTAKGETL LDTIDNLSAM AADIFVVRHS 

       130        140        150        160        170        180 
ESGAPYLIAQ HVAPHVHVVN AGDGRHSHPT QGLLDMYTIR HYKKDFSNLT VAIVGDVLHS 

       190        200        210        220        230        240 
RVARSDIHAL TTLGAAEVRV VGPRTLVPSD MAQMGVRVFH NLEEGIKGCD VVITLRLQNE 

       250        260        270        280        290        300 
RMSGALLPSS QEYFKSFGLT PEKLRLAKPD AIVMHPGPIN RGVEIDSAVV DGPQAVILPQ 

       310        320 
VTFGIAVRMA VMSIVAGNEA 

« Hide

References

[1]"Complete sequence of chromosome 1 of Acidovorax sp. JS42."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000539 Genomic DNA. Translation: ABM43682.1.
RefSeqYP_987758.1.

3D structure databases

SMRA1WBQ7. Positions 16-318.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1WBQ7.

Genome annotation databases

GeneID4672401.
GenomeReviewsGene locus Ajs_3570 in contig CP000539_GR.
KEGGajs:Ajs_3570.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0540.
HOGENOMHBG579429.
OMAVMMLRVQ.

Family and domain databases

HAMAPMF_00001. Asp_carb_tr.
[Tree]
InterProIPR006132. Asp/Orn_carbamoyltranf_P_bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082. Asp_carbamoyltransf_euk.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00101. ATCASE.
TIGRFAMsTIGR00670. asp_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRB_ACISJ
AccessionPrimary (citable) accession number: A1WBQ7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 6, 2007
Last modified: February 9, 2010
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents