A1W9P4 (GCP_ACISJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	Ajs_2828

Organism

Acidovorax sp. (strain JS42) [Complete proteome] [HAMAP]

Taxonomic identifier

232721 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.
Sequence caution	The sequence ABM42969.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303244

Sequences

	Sequence		Length	Mass (Da)
	A1W9P4 [UniParc]. Last modified September 11, 2007. Version 2. Checksum: 003FE9B629DDF415	FASTA	349	36,677
	10 20 30 40 50 60 MSQLILGIES SCDETGVALV RAGEGGAVPV LLAHALHSQI DMHQAYGGVV PELASRDHIR 70 80 90 100 110 120 RVLPLTREVL RESGERLEDV DVVAYTRGPG LAGALLVGAG VACALGAALD KPVLGVHHLE 130 140 150 160 170 180 GHLLSPFLSS DPPEFPFVAL LVSGGHTQLM RVEGVGRYEI LGETIDDAAG EAFDKSAKLM 190 200 210 220 230 240 GLGYPGGPAL SRLAEQGSAT AFKLPRPLLH SGDLDFSFAG LKTAVLTQAK KLGDELTARK 250 260 270 280 290 300 ADLAASTEAA IVEVLVKKTL AALQKTGLQR VVVAGGVGAN RHLRAQLNAA CARAKVRVHY 310 320 330 340 PELHLCTDNG AMIAMAAAMR LQAGQQQPNR DYAFDVKPRW PLDAITLAA

References

[1]

"Complete sequence of chromosome 1 of Acidovorax sp. JS42." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JS42.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000539 Genomic DNA. Translation: ABM42969.1. Different initiation.
RefSeq	YP_987045.1. NC_008782.1.
3D structure databases
ProteinModelPortal	A1W9P4.
ModBase	Search...
Protein-protein interaction databases
STRING	A1W9P4.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4673437.
GenomeReviews	Gene locus Ajs_2828 in contig CP000539_GR.
KEGG	ajs:Ajs_2828.
PATRIC	20691015. VBIAciSp27161_3028.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	ASP232721:AJS_2828-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_ACISJ

Accession

Primary (citable) accession number: A1W9P4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program