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A1W9B0 (TYPH2_ACISJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase 2

EC=2.4.2.4
Alternative name(s):
TdRPase 2
Gene names
Ordered Locus Names:Ajs_2690
OrganismAcidovorax sp. (strain JS42) [Complete proteome] [HAMAP]
Taxonomic identifier232721 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 513513Putative thymidine phosphorylase 2 HAMAP-Rule MF_00703
PRO_0000314695

Sequences

Sequence LengthMass (Da)Tools
A1W9B0 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: EEA4E3707AC03BAE

FASTA51353,719
        10         20         30         40         50         60 
MTAQMHEAGR TKEAGNRLQA WRTGIDTYQE PVVYMRRDCP VCRSEGFTTQ ARVQLTAGGR 

        70         80         90        100        110        120 
SIVATLSVVD GDWLAENVAG LSESAWASLG AQPGEPVAVT HAPPLDSLSH VRAKVYGNSL 

       130        140        150        160        170        180 
GDAQFGAIIS DVAAGRYSDL HLATFITACA GDRLDLAETL SLTKAMIAVG DRIDWGRPLV 

       190        200        210        220        230        240 
VDKHCVGGLP GNRTTLLVVP IVTACGLMMP KTSSRAITSP AGTADTMEVL APVNLDVPSM 

       250        260        270        280        290        300 
RRVVERTGGC IVWGGSVRLS PADDILIRVE RPLDLDSEGQ LVASVLSKKA AAGSTHVLID 

       310        320        330        340        350        360 
LPVGATAKVR SAHAAASLGR RLQEVGGAIG LQVFLRVTDG EQPVGRGIGP ALEARDVLAV 

       370        380        390        400        410        420 
LQGTREAPAD LRERALRLAA DILEMGGAAP AGGGLKLATE VLADGRAWAK FQAICSEQGG 

       430        440        450        460        470        480 
LRSLPMAAHL HTVESPGTGR VTRIDNRLLA RAAKLAGAPT APAAGIDVHA RLGDRVEAGQ 

       490        500        510 
PLFTLHAQAP GELAYALEFV RARPPIFQIS ENV 

« Hide

References

[1]"Complete sequence of chromosome 1 of Acidovorax sp. JS42."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JS42.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000539 Genomic DNA. Translation: ABM42835.1.
RefSeqYP_986911.1. NC_008782.1.

3D structure databases

ProteinModelPortalA1W9B0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING232721.Ajs_2690.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM42835; ABM42835; Ajs_2690.
GeneID4671304.
KEGGajs:Ajs_2690.
PATRIC20690733. VBIAciSp27161_2891.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OMAIHYNDEA.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycASP232721:GHWE-2727-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH2_ACISJ
AccessionPrimary (citable) accession number: A1W9B0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families