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A1W9B0

- TYPH2_ACISJ

UniProt

A1W9B0 - TYPH2_ACISJ

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Protein
Putative thymidine phosphorylase 2
Gene
Ajs_2690
Organism
Acidovorax sp. (strain JS42)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciASP232721:GHWE-2727-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase 2 (EC:2.4.2.4)
Alternative name(s):
TdRPase 2
Gene namesi
Ordered Locus Names:Ajs_2690
OrganismiAcidovorax sp. (strain JS42)
Taxonomic identifieri232721 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000000645: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 513513Putative thymidine phosphorylase 2UniRule annotation
PRO_0000314695Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi232721.Ajs_2690.

Structurei

3D structure databases

ProteinModelPortaliA1W9B0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiIHYNDEA.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1W9B0-1 [UniParc]FASTAAdd to Basket

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MTAQMHEAGR TKEAGNRLQA WRTGIDTYQE PVVYMRRDCP VCRSEGFTTQ    50
ARVQLTAGGR SIVATLSVVD GDWLAENVAG LSESAWASLG AQPGEPVAVT 100
HAPPLDSLSH VRAKVYGNSL GDAQFGAIIS DVAAGRYSDL HLATFITACA 150
GDRLDLAETL SLTKAMIAVG DRIDWGRPLV VDKHCVGGLP GNRTTLLVVP 200
IVTACGLMMP KTSSRAITSP AGTADTMEVL APVNLDVPSM RRVVERTGGC 250
IVWGGSVRLS PADDILIRVE RPLDLDSEGQ LVASVLSKKA AAGSTHVLID 300
LPVGATAKVR SAHAAASLGR RLQEVGGAIG LQVFLRVTDG EQPVGRGIGP 350
ALEARDVLAV LQGTREAPAD LRERALRLAA DILEMGGAAP AGGGLKLATE 400
VLADGRAWAK FQAICSEQGG LRSLPMAAHL HTVESPGTGR VTRIDNRLLA 450
RAAKLAGAPT APAAGIDVHA RLGDRVEAGQ PLFTLHAQAP GELAYALEFV 500
RARPPIFQIS ENV 513
Length:513
Mass (Da):53,719
Last modified:February 6, 2007 - v1
Checksum:iEEA4E3707AC03BAE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000539 Genomic DNA. Translation: ABM42835.1.
RefSeqiWP_011805859.1. NC_008782.1.
YP_986911.1. NC_008782.1.

Genome annotation databases

EnsemblBacteriaiABM42835; ABM42835; Ajs_2690.
GeneIDi4671304.
KEGGiajs:Ajs_2690.
PATRICi20690733. VBIAciSp27161_2891.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000539 Genomic DNA. Translation: ABM42835.1 .
RefSeqi WP_011805859.1. NC_008782.1.
YP_986911.1. NC_008782.1.

3D structure databases

ProteinModelPortali A1W9B0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 232721.Ajs_2690.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM42835 ; ABM42835 ; Ajs_2690 .
GeneIDi 4671304.
KEGGi ajs:Ajs_2690.
PATRICi 20690733. VBIAciSp27161_2891.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi IHYNDEA.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci ASP232721:GHWE-2727-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Acidovorax sp. JS42."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
    , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JS42.

Entry informationi

Entry nameiTYPH2_ACISJ
AccessioniPrimary (citable) accession number: A1W9B0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: September 3, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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