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A1W9B0

- TYPH2_ACISJ

UniProt

A1W9B0 - TYPH2_ACISJ

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Protein

Putative thymidine phosphorylase 2

Gene

Ajs_2690

Organism
Acidovorax sp. (strain JS42)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciASP232721:GHWE-2727-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase 2UniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPase 2UniRule annotation
Gene namesi
Ordered Locus Names:Ajs_2690
OrganismiAcidovorax sp. (strain JS42)
Taxonomic identifieri232721 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000000645: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 513513Putative thymidine phosphorylase 2PRO_0000314695Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi232721.Ajs_2690.

Structurei

3D structure databases

ProteinModelPortaliA1W9B0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiIHYNDEA.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1W9B0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAQMHEAGR TKEAGNRLQA WRTGIDTYQE PVVYMRRDCP VCRSEGFTTQ
60 70 80 90 100
ARVQLTAGGR SIVATLSVVD GDWLAENVAG LSESAWASLG AQPGEPVAVT
110 120 130 140 150
HAPPLDSLSH VRAKVYGNSL GDAQFGAIIS DVAAGRYSDL HLATFITACA
160 170 180 190 200
GDRLDLAETL SLTKAMIAVG DRIDWGRPLV VDKHCVGGLP GNRTTLLVVP
210 220 230 240 250
IVTACGLMMP KTSSRAITSP AGTADTMEVL APVNLDVPSM RRVVERTGGC
260 270 280 290 300
IVWGGSVRLS PADDILIRVE RPLDLDSEGQ LVASVLSKKA AAGSTHVLID
310 320 330 340 350
LPVGATAKVR SAHAAASLGR RLQEVGGAIG LQVFLRVTDG EQPVGRGIGP
360 370 380 390 400
ALEARDVLAV LQGTREAPAD LRERALRLAA DILEMGGAAP AGGGLKLATE
410 420 430 440 450
VLADGRAWAK FQAICSEQGG LRSLPMAAHL HTVESPGTGR VTRIDNRLLA
460 470 480 490 500
RAAKLAGAPT APAAGIDVHA RLGDRVEAGQ PLFTLHAQAP GELAYALEFV
510
RARPPIFQIS ENV
Length:513
Mass (Da):53,719
Last modified:February 6, 2007 - v1
Checksum:iEEA4E3707AC03BAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000539 Genomic DNA. Translation: ABM42835.1.
RefSeqiWP_011805859.1. NC_008782.1.
YP_986911.1. NC_008782.1.

Genome annotation databases

EnsemblBacteriaiABM42835; ABM42835; Ajs_2690.
GeneIDi4671304.
KEGGiajs:Ajs_2690.
PATRICi20690733. VBIAciSp27161_2891.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000539 Genomic DNA. Translation: ABM42835.1 .
RefSeqi WP_011805859.1. NC_008782.1.
YP_986911.1. NC_008782.1.

3D structure databases

ProteinModelPortali A1W9B0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 232721.Ajs_2690.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM42835 ; ABM42835 ; Ajs_2690 .
GeneIDi 4671304.
KEGGi ajs:Ajs_2690.
PATRICi 20690733. VBIAciSp27161_2891.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi IHYNDEA.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci ASP232721:GHWE-2727-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 1 of Acidovorax sp. JS42."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
    , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JS42.

Entry informationi

Entry nameiTYPH2_ACISJ
AccessioniPrimary (citable) accession number: A1W9B0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 1, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3