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Protein
Submitted name:

ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase module

Gene

Ajs_2523

Organism
Acidovorax sp. (strain JS42)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciASP232721:GHWE-2555-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase moduleImported (EC:6.5.1.1Imported)
Gene namesi
Ordered Locus Names:Ajs_2523Imported
OrganismiAcidovorax sp. (strain JS42)Imported
Taxonomic identifieri232721 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
ProteomesiUP000000645 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi232721.Ajs_2523.

Structurei

3D structure databases

ProteinModelPortaliA1W8V8.
SMRiA1W8V8. Positions 542-829.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol_dom.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1W8V8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRKDPLAVY KQKRNFAVTP EPADGGAQSQ ALQYVIQKHW ASRLHYDLRL
60 70 80 90 100
ELDGTMKSWA VPKGPSYDPA DKRMAVQVED HPISYNQFEG QIPPRQYGAG
110 120 130 140 150
RVIIWDRGYW VPQGNPREDY RKGKLKFEIH GHKLHGHWTL VRMHGRDDDK
160 170 180 190 200
QPPWLLIKEC DGLERAAEEF NVVDEMPDSV ADQPPVAPPA RAFAQRAGPA
210 220 230 240 250
QIQPTAAAVP WTSAPTAPLP DQLSPQLATL VDGPPADLTQ WLWELKFDGY
260 270 280 290 300
RMLARVQRGK ARLYTRNGND WTARMPALAQ ALAALPLSSA WIDGEVLVLD
310 320 330 340 350
AQGVPDFQAL QNAFDGRSTD ALVFYAFDLP YAHGRDLRQM PLAERRALLR
360 370 380 390 400
SVLQPASSDR VRFSEAFEAR PADLVASACR LGFEGVIGKR KDSVYASRRS
410 420 430 440 450
TDWIKLKCSH RQEFVIGGYT DPQGSRTGIG SLLLGVHDEG GALRYAGNVG
460 470 480 490 500
TGFSERVLAD LARRLGALRT QDSPFAQPRS IPRKVHWVRP TLVAEVSFAE
510 520 530 540 550
WTKEGKVRHA VFRGLRDDKP AAAIVHEEPA HLQGAAPSRA ARVGGLQVTS
560 570 580 590 600
PARVVDPSTG FTKLDLVRYY ATVAPLMLPH LQGRPVSLLR APQGLEGELF
610 620 630 640 650
FQKHLDTGAL DGVSALSPDL DPGHPPLLEV ATAQGLLSAA QMNTVEFHTW
660 670 680 690 700
NARKDRIERP NRITFDLDPG EGVPWAHVQE GAALVRLMLT ELGLPSFLKT
710 720 730 740 750
SGGKGLHVVV PIKRLHGWDA VKDFSQAVVQ HLARTLPQRF VAKSGPRNRV
760 770 780 790 800
GKIFVDYLRN GFGATTACAW TARARPGMGV SVPVAWQELD ALTGGAHWTV
810 820 830
QTVDRRLKTG NGPWSGYDEA AVSIGPAIKA LGEKRHT
Length:837
Mass (Da):92,211
Last modified:February 6, 2007 - v1
Checksum:i89D8CDCB825940E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000539 Genomic DNA. Translation: ABM42683.1.
RefSeqiWP_011805722.1. NC_008782.1.
YP_986759.1. NC_008782.1.

Genome annotation databases

EnsemblBacteriaiABM42683; ABM42683; Ajs_2523.
KEGGiajs:Ajs_2523.
PATRICi20690405. VBIAciSp27161_2732.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000539 Genomic DNA. Translation: ABM42683.1.
RefSeqiWP_011805722.1. NC_008782.1.
YP_986759.1. NC_008782.1.

3D structure databases

ProteinModelPortaliA1W8V8.
SMRiA1W8V8. Positions 542-829.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi232721.Ajs_2523.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM42683; ABM42683; Ajs_2523.
KEGGiajs:Ajs_2523.
PATRICi20690405. VBIAciSp27161_2732.

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Enzyme and pathway databases

BioCyciASP232721:GHWE-2555-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol_dom.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 1 of Acidovorax sp. JS42."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
    , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JS42Imported.

Entry informationi

Entry nameiA1W8V8_ACISJ
AccessioniPrimary (citable) accession number: A1W8V8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: April 29, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.