Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A1W8S8

- PNCB_ACISJ

UniProt

A1W8S8 - PNCB_ACISJ

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Acidovorax sp. (strain JS42)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

    Catalytic activityi

    Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
    3. nicotinate phosphoribosyltransferase activity Source: InterPro

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway
    2. nicotinate nucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Enzyme and pathway databases

    BioCyciASP232721:GHWE-2524-MONOMER.
    UniPathwayiUPA00253; UER00457.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
    Short name:
    NAPRTaseUniRule annotation
    Gene namesi
    Name:pncBUniRule annotation
    Ordered Locus Names:Ajs_2492
    OrganismiAcidovorax sp. (strain JS42)
    Taxonomic identifieri232721 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
    ProteomesiUP000000645: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 398398Nicotinate phosphoribosyltransferasePRO_1000129460Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi232721.Ajs_2492.

    Structurei

    3D structure databases

    ProteinModelPortaliA1W8S8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAPRTase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1488.
    HOGENOMiHOG000284928.
    KOiK00763.
    OMAiSIVCKVI.
    OrthoDBiEOG6X10XB.

    Family and domain databases

    HAMAPiMF_00570. NAPRTase.
    InterProiIPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view]
    PANTHERiPTHR11098. PTHR11098. 1 hit.
    PfamiPF04095. NAPRTase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000484. NAPRT. 1 hit.
    SUPFAMiSSF51690. SSF51690. 1 hit.
    TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1W8S8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIITSLLDTD LYKFTMMQVV LHQFPGAQVE YRFKCRNPGV ELAPFVSEIR    50
    DEIRALCSLQ FQDAELAYLR SLRFIKSDFV DFLGLFRLNE KYIRVSALPS 100
    GEIDITITGP WLHTILFEIP VLAIVNEVYF RNTQKVPDFP EGRRRLEAKI 150
    GQLQQPGLDS LKIADYGTRR RFSRAWHEEV LRVLCVRLGS DDRRGAPGQF 200
    AGTSNVLYAM KLGVTPLGTM AHEYLQACQS LGPRLRDSQV FGFEMWAKEY 250
    RGDLGIALSD VYGMSAFLRD FDLYFCKLFD GARHDSGDPF AWGERLLQHY 300
    RDNRVDPLTK TLIFSDALTV PRIIELYQRF NGRCQLAFGI GTNLTNDLGY 350
    EPLQIVIKMT RCNGQPVAKL SDAPGKNMCN DEKYLAYLRQ VFEIPSPQ 398
    Length:398
    Mass (Da):45,542
    Last modified:February 6, 2007 - v1
    Checksum:iDA75F212BA1D6045
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000539 Genomic DNA. Translation: ABM42653.1.
    RefSeqiYP_986729.1. NC_008782.1.

    Genome annotation databases

    EnsemblBacteriaiABM42653; ABM42653; Ajs_2492.
    GeneIDi4673616.
    KEGGiajs:Ajs_2492.
    PATRICi20690339. VBIAciSp27161_2699.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000539 Genomic DNA. Translation: ABM42653.1 .
    RefSeqi YP_986729.1. NC_008782.1.

    3D structure databases

    ProteinModelPortali A1W8S8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 232721.Ajs_2492.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABM42653 ; ABM42653 ; Ajs_2492 .
    GeneIDi 4673616.
    KEGGi ajs:Ajs_2492.
    PATRICi 20690339. VBIAciSp27161_2699.

    Phylogenomic databases

    eggNOGi COG1488.
    HOGENOMi HOG000284928.
    KOi K00763.
    OMAi SIVCKVI.
    OrthoDBi EOG6X10XB.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00457 .
    BioCyci ASP232721:GHWE-2524-MONOMER.

    Family and domain databases

    HAMAPi MF_00570. NAPRTase.
    InterProi IPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view ]
    PANTHERi PTHR11098. PTHR11098. 1 hit.
    Pfami PF04095. NAPRTase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000484. NAPRT. 1 hit.
    SUPFAMi SSF51690. SSF51690. 1 hit.
    TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome 1 of Acidovorax sp. JS42."
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.
      , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JS42.

    Entry informationi

    Entry nameiPNCB_ACISJ
    AccessioniPrimary (citable) accession number: A1W8S8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3