Reviewed, UniProtKB/Swiss-Prot A1W8S8 (PNCB_ACISJ)

Names and origin

Protein names

Recommended name:
    Nicotinate phosphoribosyltransferase
      Short name=NAPRTase
    EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	Ajs_2492

Organism

Acidovorax sp. (strain JS42) [Complete proteome] [HAMAP]

Taxonomic identifier

232721 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 398	398	Nicotinate phosphoribosyltransferase HAMAP MF_00570		PRO_1000129460

Sequences

	Sequence		Length	Mass (Da)
	A1W8S8-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: DA75F212BA1D6045	FASTA	398	45,542
	10 20 30 40 50 60 MIITSLLDTD LYKFTMMQVV LHQFPGAQVE YRFKCRNPGV ELAPFVSEIR DEIRALCSLQ 70 80 90 100 110 120 FQDAELAYLR SLRFIKSDFV DFLGLFRLNE KYIRVSALPS GEIDITITGP WLHTILFEIP 130 140 150 160 170 180 VLAIVNEVYF RNTQKVPDFP EGRRRLEAKI GQLQQPGLDS LKIADYGTRR RFSRAWHEEV 190 200 210 220 230 240 LRVLCVRLGS DDRRGAPGQF AGTSNVLYAM KLGVTPLGTM AHEYLQACQS LGPRLRDSQV 250 260 270 280 290 300 FGFEMWAKEY RGDLGIALSD VYGMSAFLRD FDLYFCKLFD GARHDSGDPF AWGERLLQHY 310 320 330 340 350 360 RDNRVDPLTK TLIFSDALTV PRIIELYQRF NGRCQLAFGI GTNLTNDLGY EPLQIVIKMT 370 380 390 RCNGQPVAKL SDAPGKNMCN DEKYLAYLRQ VFEIPSPQ

References

[1]

"Complete sequence of chromosome 1 of Acidovorax sp. JS42." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000539 Genomic DNA. Translation: ABM42653.1.
RefSeq	YP_986729.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1W8S8.
Genome annotation databases
GeneID	4673616.
GenomeReviews	Gene locus Ajs_2492 in contig CP000539_GR.
KEGG	ajs:Ajs_2492.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ALTDTFG.
Family and domain databases
HAMAP	MF_00570. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. [Graphical view]
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_ACISJ

Accession

Primary (citable) accession number: A1W8S8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)