Reviewed, UniProtKB/Swiss-Prot A1W6H4 (AROC_ACISJ)

Names and origin

Protein names

Recommended name:
    Chorismate synthase
    EC=4.2.3.5
Alternative name(s):
    5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	Ajs_1658

Organism

Acidovorax sp. (strain JS42) [Complete proteome] [HAMAP]

Taxonomic identifier

232721 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 366	366	Chorismate synthase HAMAP MF_00300		PRO_1000022455

Sequences

	Sequence		Length	Mass (Da)
	A1W6H4-1 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 74CA46FA55F805E7	FASTA	366	38,785
	10 20 30 40 50 60 MSGNTLGTLF CVTNFGESHG PAIGCVIDGC PPGMELSEAD IQADLDRRRP GTSRHVTQRN 70 80 90 100 110 120 EPDAVEILSG VYEGKTTGTP IALLIRNTDQ RSKDYGNIAQ SFRPGHADYA YWHKYGLRDP 130 140 150 160 170 180 RGGGRSSARL TAPTVAAGAV AKKWLAEKYG TRFRACMTQL GELPIPFESW EHVPHNPFFA 190 200 210 220 230 240 PVADVQAYED YMDALRKSGD SCGARIRVQA TGVPVGLGDP LYDKLDADIA HVMMGLNAVK 250 260 270 280 290 300 GVEIGAGFAS VAQRGTTHGD SLTPTGFASN NAGGVLGGIS TGQDIEVSLA IKPTSSIISP 310 320 330 340 350 360 RESIDIHGQS TEVITKGRHD PCVGIRAAPI AEALLALVIM DHALRHRAQC GDVVQAVAPI PAVRLG

References

[1]

"Complete sequence of chromosome 1 of Acidovorax sp. JS42." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000539 Genomic DNA. Translation: ABM41849.1.
RefSeq	YP_985925.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1W6H4.
Genome annotation databases
GeneID	4670993.
GenomeReviews	Gene locus Ajs_1658 in contig CP000539_GR.
KEGG	ajs:Ajs_1658.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SRFTTQR.
Family and domain databases
HAMAP	MF_00300. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
ProDom	PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00033. aroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_ACISJ

Accession

Primary (citable) accession number: A1W6H4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)