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A1W6G8 (A1W6G8_ACISJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Ajs_1652
OrganismAcidovorax sp. (strain JS42) [Complete proteome] [HAMAP]
Taxonomic identifier232721 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2201Iron By similarity HAMAP MF_00323
Metal binding3011Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A1W6G8 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 60017B791040B9DF

FASTA35238,894
        10         20         30         40         50         60 
MPASPSHHAA QTASASSIQT AAARESTAIL LCNLGTPDAP TAPALRRYLA QFLGDPRVVE 

        70         80         90        100        110        120 
IPRALWLPLL YGIILRTRPA KSAAKYASIW TEEGSPLAVW TAKQAVMLRG WLGEAGQPVR 

       130        140        150        160        170        180 
VLPAMRYGQP AIGAQLQVLQ DAGVRRVLVL PLYPQYSATT TASVFDDVAA WVRRSRCFPE 

       190        200        210        220        230        240 
LRFVNDYHDH PDYIAALAQS VRAHWQREGG PADKLVMSFH GIPERNVRLG DPYAEQCRNT 

       250        260        270        280        290        300 
ARLLAQALGL GEDRYLLTFQ SRFGKARWLE PYTEPSLVAL AQGGTRRVDV MCPGFTSDCL 

       310        320        330        340        350 
ETLEEINQEA REAFLHAGGQ DFRYIPCLND NPAWITALSR IAQQHLAGWS QP

« Hide

References

[1]"Complete sequence of chromosome 1 of Acidovorax sp. JS42."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000539 Genomic DNA. Translation: ABM41843.1.
RefSeqYP_985919.1. NC_008782.1.

3D structure databases

ProteinModelPortalA1W6G8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1W6G8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4670924.
GenomeReviewsGene locus Ajs_1652 in contig CP000539_GR.
KEGGajs:Ajs_1652.
PATRIC20688628. VBIAciSp27161_1852.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBA1W6G8.
ProtClustDBCLSK732540.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1W6G8_ACISJ
AccessionPrimary (citable) accession number: A1W6G8
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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