Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A1W631 (TYPH1_ACISJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase 1

EC=2.4.2.4
Alternative name(s):
TdRPase 1
Gene names
Ordered Locus Names:Ajs_1507
OrganismAcidovorax sp. (strain JS42) [Complete proteome] [HAMAP]
Taxonomic identifier232721 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax

Protein attributes

Sequence length511 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 511511Putative thymidine phosphorylase 1 HAMAP-Rule MF_00703
PRO_0000314694

Sequences

Sequence LengthMass (Da)Tools
A1W631 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 4F0DA967C6F9962D

FASTA51153,758
        10         20         30         40         50         60 
MSDHAMNEQR DHDTRLRAWR TGIDTYQEPI VYMRSDCVVC RSEGFTTQTR VLLTAGTRSA 

        70         80         90        100        110        120 
VATLNVVEGN WLAPGVAGLS EAAWHALDPA ADAWINVSYA PTLDSLSHVR AKVYGHRLDA 

       130        140        150        160        170        180 
GAFNAVIGDV AAGRYSDLYL AAFVTACAGD RLDLSETVAL TRAMVAVGHR LDWGRETVVD 

       190        200        210        220        230        240 
KHCVGGLPGN RTTLLVVPIV AACGLTMPKT SSRAITSPAG TADTMEVLAP VNLDIAAMRR 

       250        260        270        280        290        300 
TVERTGGCIV WGGSVRLSPA DDVLIRVERP LDLDSEGQLV ASVLSKKAAA GSTHVLIDLP 

       310        320        330        340        350        360 
VGPTAKVRST EAAQSLGRRL VEVGRAIGLQ VTLRITDGLQ PVGRGVGPAL EARDVLAVLR 

       370        380        390        400        410        420 
GQADAPDDLR QRALRLAGDI LELGGAAPNG SGLQLAAEVL ADGRAWAKFQ AICEAQGGLR 

       430        440        450        460        470        480 
EVPVTPYRQV ITAAVAGRVA AIDNRVLARA AKLAGAPKAP AAGVDVHARI GDPVQAGQPL 

       490        500        510 
FTLHAQTAGE LDYAGHFVDT RPPIFQISEE A 

« Hide

References

[1]"Complete sequence of chromosome 1 of Acidovorax sp. JS42."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JS42.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000539 Genomic DNA. Translation: ABM41706.1.
RefSeqYP_985782.1. NC_008782.1.

3D structure databases

ProteinModelPortalA1W631.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING232721.Ajs_1507.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM41706; ABM41706; Ajs_1507.
GeneID4671546.
KEGGajs:Ajs_1507.
PATRIC20688342. VBIAciSp27161_1713.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OMAFICISEG.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycASP232721:GHWE-1524-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH1_ACISJ
AccessionPrimary (citable) accession number: A1W631
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: May 14, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families