A1W538 (DCD_ACISJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Ajs_1130

Organism

Acidovorax sp. (strain JS42) [Complete proteome] [HAMAP]

Taxonomic identifier

232721 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Acidovorax

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009671

Sequences

	Sequence		Length	Mass (Da)
	A1W538 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 7D7B393540D98638	FASTA	188	21,378
	10 20 30 40 50 60 MSIKSDKWIR RMAEQHGMIE PFEPGQIRQQ DGRKIISYGT SSYGYDIRCA REFKVFTNIH 70 80 90 100 110 120 STVVDPKNFD EKSFVDFEGD YCIIPPNSFA LARTVEYFRI PRDVLTVCLG KSTYARCGII 130 140 150 160 170 180 VNVTPFEPEW EGYVTLEFSN TTPLPAKIYA GEGCAQVLFF QGDEECAVSY KDRNGKYQGQ HGVTLPKA

References

[1]

"Complete sequence of chromosome 1 of Acidovorax sp. JS42." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JS42.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000539 Genomic DNA. Translation: ABM41363.1.
RefSeq	YP_985439.1. NC_008782.1.
3D structure databases
ProteinModelPortal	A1W538.
ModBase	Search...
Protein-protein interaction databases
STRING	A1W538.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4671723.
GenomeReviews	Gene locus Ajs_1130 in contig CP000539_GR.
KEGG	ajs:Ajs_1130.
PATRIC	20687554. VBIAciSp27161_1328.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	A1W538.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	ASP232721:AJS_1130-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_ACISJ

Accession

Primary (citable) accession number: A1W538

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program