A1W0A5 (CHEY_CAMJJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chemotaxis protein CheY homolog

Gene names

Name:	cheY
Ordered Locus Names:	CJJ81176_1136

Organism

Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) [Complete proteome] [HAMAP]

Taxonomic identifier

354242 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter › Campylobacter jejuni › Campylobacter jejuni subsp. jejuni

Protein attributes

Sequence length	130 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation By similarity.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Contains 1 response regulatory domain.
Sequence caution	The sequence AAC44858.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Chemotaxis Flagellar rotation Two-component regulatory system
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW ciliary or flagellar motility Inferred from electronic annotation. Source: UniProtKB-KW intracellular signal transduction Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphorelay response regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 130	130	Chemotaxis protein CheY homolog		PRO_0000281899
Regions
	Domain	1 – 120	120	Response regulatory
Sites
	Metal binding	7	1	Magnesium By similarity
	Metal binding	8	1	Magnesium By similarity
	Metal binding	53	1	Magnesium By similarity
	Metal binding	55	1	Magnesium; via carbonyl oxygen By similarity
Amino acid modifications
	Modified residue	53	1	4-aspartylphosphate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1W0A5 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 41634D8ADE6C5081	FASTA	130	14,437
	10 20 30 40 50 60 MKLLVVDDSS TMRRIIKNTL TRLGHDDVLE AEHGVEAWDL LTKNEDVKVL ITDWNMPEMN 70 80 90 100 110 120 GLELVKKVRA EKKYEDMPII MVTTEGGKAE VITALKAGVN NYIVKPFTPQ VLKEKLEDVL 130 GTGSGEGAAE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"CheY-mediated modulation of Campylobacter jejuni virulence." Yao R., Burr D.H., Guerry P. Mol. Microbiol. 23:1021-1032(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Fouts D.E., Nelson K.E., Sebastian Y. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 81-176.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U62038 Genomic DNA. Translation: AAC44858.1. Different initiation. CP000538 Genomic DNA. Translation: EAQ72145.1.
RefSeq	YP_001000796.1. NC_008787.1.
3D structure databases
ProteinModelPortal	A1W0A5.
ModBase	Search...
Protein-protein interaction databases
STRING	354242.CJJ81176_1136.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EAQ72145; EAQ72145; CJJ81176_1136.
GeneID	4682456.
KEGG	cjj:CJJ81176_1136.
PATRIC	20052245. VBICamJej103413_1135.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0784.
HOGENOM	HOG000034820.
KO	K03413.
OMA	DVLITDW.
ProtClustDB	CLSK872349.
Family and domain databases
InterPro	IPR011006. CheY-like_superfamily. IPR001789. Sig_transdc_resp-reg_receiver. [Graphical view]
Pfam	PF00072. Response_reg. 1 hit. [Graphical view]
SMART	SM00448. REC. 1 hit. [Graphical view]
SUPFAM	SSF52172. CheY_like. 1 hit.
PROSITE	PS50110. RESPONSE_REGULATORY. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CHEY_CAMJJ

Accession

Primary (citable) accession number: A1W0A5
Secondary accession number(s): P71129

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 3, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program