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A1VZY3 (A1VZY3_CAMJJ) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515

EC=4.2.1.24 RuleBase RU000515
Gene names
Name:hemB EMBL EAQ72062.1
Ordered Locus Names:CJJ81176_1013
OrganismCampylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) [Complete proteome] [HAMAP]
Taxonomic identifier354242 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. RuleBase RU000515 PIRSR PIRSR001415-3

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1961Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2491Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1191Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1211Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1291Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2341Magnesium By similarity PIRSR PIRSR001415-5
Binding site2061Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2181Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2751Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3141Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
A1VZY3 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 610B4A4EDE63AEBB

FASTA32736,440
        10         20         30         40         50         60 
MFKRFRRLRL NENLRAMVRE NSLSVNDLIY PLFVVNGTGI KKEISSMPDV FQMSLDEILK 

        70         80         90        100        110        120 
ECQNVVNLGI KAIILFGVLE NEKKDSCGSD ALDDEGLVAR SIREIKKNFP DLFIISDLCF 

       130        140        150        160        170        180 
CEYTDHGHCG IIDPKTKSVD NDVTLEISAK QALVHARAGV DMIAPSGMMD GIITTLRKAL 

       190        200        210        220        230        240 
DKEGFENLPI MAYSTKFASS YYGPFRDVAE SAPSYGDRKS YQMDFANGKE ALEESLEDEA 

       250        260        270        280        290        300 
QGADILMVKP ALAYLDVVKE ISLHSNLPLC VYNVSGEYAM LKAAKNAGVI DYEKVLYETM 

       310        320 
IAFKRAGAKL IITYHAKELA KMLKGEK 

« Hide

References

[1]Fouts D.E., Nelson K.E., Sebastian Y.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000538 Genomic DNA. Translation: EAQ72062.1.
RefSeqYP_001000674.1. NC_008787.1.

3D structure databases

ProteinModelPortalA1VZY3.
SMRA1VZY3. Positions 1-323.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1VZY3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4682926.
GenomeReviewsGene locus CJJ81176_1013 in contig CP000538_GR.
KEGGcjj:CJJ81176_1013.
PATRIC20051997. VBICamJej103413_1012.
TIGRCJJ81176_1013.

Phylogenomic databases

eggNOGCOG0113.
HOGENOMHBG285270.
OMATEAYNEN.
PhylomeDBA1VZY3.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1VZY3_CAMJJ
AccessionPrimary (citable) accession number: A1VZY3
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)