A1VY11 (A1VY11_CAMJJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthetase EMBL EAQ73067.1
EC=2.4.1.182 EMBL EAQ73067.1

Gene names

Name:	lpxB EMBL EAQ73067.1
Ordered Locus Names:	CJJ81176_0314

Organism

Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176) [Complete proteome] [HAMAP]

Taxonomic identifier

354242 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL EAQ73067.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1VY11 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 45B276D10E1ACF2F	FASTA	364	41,668
	10 20 30 40 50 60 MKTFLVCALE PSANLHLKEV LKAYKKDFGE FELHGIYDES LCKEFDLNSK PLYSSHEFSA 70 80 90 100 110 120 MGFIEVLPLI FKAKKAIKEL INLSFAQKIN GILCIDSPAF NIPFAKALKK AGSKIPRIYY 130 140 150 160 170 180 ILPQVWAWKK GRIPIIESHF DILASILPFD NQFFNKSTYV GHPLLDEIKE FKNQEDINHT 190 200 210 220 230 240 FSKKDDEKTI AFLPGSRRSE IRRLMPIFKE LSQKFKGEKI LCVPSFNLEK LEIYGDISEF 250 260 270 280 290 300 KIESNTPKVL KKADFAFICS GTATLEAALV GTPFVLTYKA KAIDIFIAKL FVKLKHIGLA 310 320 330 340 350 360 NIFCDFAKKE ALNPEFLQDK VNVLNLYEAY NKYDYKAFFA KVDFLKEYLQ FGSAKNLAKI LSEI

References

[1]	Fouts D.E., Nelson K.E., Sebastian Y. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000538 Genomic DNA. Translation: EAQ73067.1.
RefSeq	YP_001000002.1. NC_008787.1.
3D structure databases
ProteinModelPortal	A1VY11.
ModBase	Search...
Protein-protein interaction databases
STRING	A1VY11.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4683657.
GenomeReviews	Gene locus CJJ81176_0314 in contig CP000538_GR.
KEGG	cjj:CJJ81176_0314.
PATRIC	20050584. VBICamJej103413_0335.
TIGR	CJJ81176_0314.
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	AEFAFIC.
PhylomeDB	A1VY11.
ProtClustDB	PRK14089.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1VY11_CAMJJ

Accession

Primary (citable) accession number: A1VY11

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)