tal

Functionⁱ

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.UniRule annotation

Catalytic activityⁱ

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.UniRule annotation

Pathwayⁱ: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

no protein annotated in this organism
Transaldolase (tal)
no protein annotated in this organism

This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	125	Schiff-base intermediate with substrateUniRule annotation		1

GO - Molecular functionⁱ

sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate metabolic process Source: InterPro
pentose-phosphate shunt Source: UniProtKB-UniPathway

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Transferase
Biological process	Pentose shunt
Ligand	Schiff base

Enzyme and pathway databases

UniPathwayⁱ	UPA00115; UER00414

UniPathwayⁱ

UPA00115; UER00414

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: TransaldolaseUniRule annotation (EC:2.2.1.2UniRule annotation)
Gene namesⁱ	Name:talUniRule annotation Ordered Locus Names:CJJ81176_0307
Organismⁱ	Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
Taxonomic identifierⁱ	354242 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter › Campylobacter jejuni › Campylobacter jejuni subsp. jejuni
Proteomesⁱ	UP000000646 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00493

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000026521	1 – 325	TransaldolaseAdd BLAST		325

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	354242.Cjejjejuni_010100001520

STRINGⁱ

354242.Cjejjejuni_010100001520

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A1VY04
SMRⁱ	A1VY04
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the transaldolase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4107V25 Bacteria COG0176 LUCA
HOGENOMⁱ	HOG000226074
KEGG Orthology (KO) More...KOⁱ	K00616
OMAⁱ	ATECYYQ

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00955 Transaldolase_like, 1 hit
Gene3Dⁱ	3.20.20.701 hit
HAMAPⁱ	MF_00493 Transaldolase_2, 1 hit
InterProⁱ	View protein in InterPro IPR013785 Aldolase_TIM IPR001585 TAL/FSA IPR004732 Transaldolase_2 IPR018225 Transaldolase_AS
PANTHERⁱ	PTHR10683 PTHR10683, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00923 TAL_FSA, 1 hit
PIRSFⁱ	PIRSF036915 Trnald_Bac_Plnt, 1 hit
TIGRFAMsⁱ	TIGR00876 tal_mycobact, 1 hit
PROSITEⁱ	View protein in PROSITE PS01054 TRANSALDOLASE_1, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A1VY04-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKNFSLWCDF IENSFLDNEF LNLLSHGING ATSNPAIFKN AILNSPIYKD 
        60         70         80         90        100
KILKLKGKKT KDIYEELAIS DIQKAADKLA PLFYQKNDGF ISIEIDPRLH 
       110        120        130        140        150
DNTTLSLGEA KRLYSAISKE NVMIKIPATK ASYEVMYELM KNGISVNATL 
       160        170        180        190        200
IFSLEQSQKC FEALNAGLVE FRKNNIALKE QNTRTPQAVI SIFVSRFDRL 
       210        220        230        240        250
LNPKAKEQNR IGILNANLAY NNIYSKNEPN IRALFASTGV KGDDLPKDYY 
       260        270        280        290        300
IKELLFENSV NTAPLDAIEA FKGKMHFKKP LMNFEIYTEL NQIISQSERE 
       310        320 
KACNDLLSDG LEQFCIAFED ILKAL

Length:325

Mass (Da):36,861

Last modified:February 6, 2007 - v1

Checksum:ⁱD62EFCDD9C1E5F26

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000538 Genomic DNA Translation: EAQ73014.1
NCBI Reference Sequences More...RefSeqⁱ	WP_002857444.1, NC_008787.1

Genome annotation databases

EnsemblBacteriaⁱ	EAQ73014; EAQ73014; CJJ81176_0307
KEGGⁱ	cjj:CJJ81176_0307

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
A1VY04	A0A0W8L8M5 A0A0W8L4P7 A0A2K1WGL0 A0A0W8LCQ5 A0A2K1WCR7 A0A0W8KQ76	Campylobacter jejuni BJ-CJGB96G25 Campylobacter jejuni BJ-CJGB95377 Campylobacter jejuni HB-CJGB-ZHX Campylobacter jejuni BJ-CJGB96114 Campylobacter jejuni HB-CJGB-ZB Campylobacter jejuni HB-CJGB-LXC	325	UniRef100_A1VY04	Cluster: Transaldolase	7

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
A1VY04	Q9PIL5 Q5HWI6 A0A0W8KY26 A0A0B6UU75 A0A218KVS0 A0A059HY31 UPI00070FF6F1 UPI000707469F D2N087 UPI0009309C93 +94	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) Campylobacter jejuni (strain RM1221) Campylobacter jejuni HB-CJGB-XWM Campylobacter jejuni subsp. jejuni Campylobacter jejuni Campylobacter jejuni K5 Campylobacter jejuni subsp. jejuni 414 Campylobacter coli Campylobacter jejuni HB-CJGB-LC Campylobacter sp. BCW_8712 And more	325	UniRef90_Q9PIL5	Cluster: Transaldolase	105

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
A1VY04	Q9PIL5 Q5HWI6 A0A0W8KY26 A0A0B6UU75 A0A218KVS0 A0A059HY31 UPI00070FF6F1 UPI000707469F D2N087 UPI0009309C93 +231	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) Campylobacter jejuni (strain RM1221) Campylobacter jejuni HB-CJGB-XWM Campylobacter jejuni subsp. jejuni Campylobacter jejuni Campylobacter jejuni K5 Campylobacter jejuni subsp. jejuni 414 Campylobacter coli Campylobacter Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.97) And more	325	UniRef50_Q9PIL5	Cluster: Transaldolase	242

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000538 Genomic DNA Translation: EAQ73014.1
NCBI Reference Sequences More...RefSeqⁱ	WP_002857444.1, NC_008787.1

3D structure databases

ProteinModelPortalⁱ	A1VY04
SMRⁱ	A1VY04
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	354242.Cjejjejuni_010100001520

STRINGⁱ

354242.Cjejjejuni_010100001520

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	EAQ73014; EAQ73014; CJJ81176_0307
KEGGⁱ	cjj:CJJ81176_0307

Phylogenomic databases

eggNOGⁱ	ENOG4107V25 Bacteria COG0176 LUCA
HOGENOMⁱ	HOG000226074
KEGG Orthology (KO) More...KOⁱ	K00616
OMAⁱ	ATECYYQ

Enzyme and pathway databases

UniPathwayⁱ	UPA00115; UER00414

UniPathwayⁱ

UPA00115; UER00414

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00955 Transaldolase_like, 1 hit
Gene3Dⁱ	3.20.20.701 hit
HAMAPⁱ	MF_00493 Transaldolase_2, 1 hit
InterProⁱ	View protein in InterPro IPR013785 Aldolase_TIM IPR001585 TAL/FSA IPR004732 Transaldolase_2 IPR018225 Transaldolase_AS
PANTHERⁱ	PTHR10683 PTHR10683, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00923 TAL_FSA, 1 hit
PIRSFⁱ	PIRSF036915 Trnald_Bac_Plnt, 1 hit
TIGRFAMsⁱ	TIGR00876 tal_mycobact, 1 hit
PROSITEⁱ	View protein in PROSITE PS01054 TRANSALDOLASE_1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	TAL_CAMJJ
Accessionⁱ	A1VY04Primary (citable) accession number: A1VY04
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
	Last sequence update:	February 6, 2007
	Last modified:	July 5, 2017
	This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A1VY04 (TAL_CAMJJ)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Transaldolase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pentose phosphate pathway

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Your basket is currently empty. ⁱ

Functionⁱ

Pathwayⁱ: pentose phosphate pathway

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ