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A1VXA2

- A1VXA2_CAMJJ

UniProt

A1VXA2 - A1VXA2_CAMJJ

Protein

Adenylosuccinate lyase

Gene

purB-1

Organism
Campylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (06 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.UniRule annotation
    N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
    2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

    GO - Biological processi

    1. purine ribonucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Biological processi

    Purine biosynthesisUniRule annotation

    Enzyme and pathway databases

    BioCyciCJEJ354242:GC51-24-MONOMER.
    UniPathwayiUPA00074; UER00132.
    UPA00075; UER00336.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Adenylosuccinate lyaseUniRule annotation (EC:4.3.2.2UniRule annotation)
    Short name:
    ASLUniRule annotation
    Alternative name(s):
    AdenylosuccinaseUniRule annotation
    Gene namesi
    Name:purB-1Imported
    Ordered Locus Names:CJJ81176_0050Imported
    OrganismiCampylobacter jejuni subsp. jejuni serotype O:23/36 (strain 81-176)Imported
    Taxonomic identifieri354242 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
    ProteomesiUP000000646: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi354242.CJJ81176_0050.

    Structurei

    3D structure databases

    ProteinModelPortaliA1VXA2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0015.
    HOGENOMiHOG000033912.
    KOiK01756.
    OMAiRNMGSTF.
    OrthoDBiEOG686NDB.

    Family and domain databases

    Gene3Di1.10.275.10. 1 hit.
    InterProiIPR019468. AdenyloSucc_lyase_C.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    IPR004769. Pur_lyase.
    [Graphical view]
    PANTHERiPTHR11444. PTHR11444. 1 hit.
    PfamiPF10397. ADSL_C. 1 hit.
    PF00206. Lyase_1. 1 hit.
    [Graphical view]
    PRINTSiPR00149. FUMRATELYASE.
    SMARTiSM00998. ADSL_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48557. SSF48557. 1 hit.
    TIGRFAMsiTIGR00928. purB. 1 hit.
    PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1VXA2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVERYSREIM AKKWDMQAKY DAWLKVELAA VKAWNKLGLI DDTDCEKILK    50
    NAKFDIARID EIEKTTKHDV IAFLTSVSES LGEESRFVHY AMTSSDCIDT 100
    AVALQIKESL ELILEDVSLL LEAIKKRALE HKNTLMVGRS HGIHGEPITF 150
    GLVLAIWYDE ISHAKELLEH AKEVISYGKI SGAMGNFAHA PLEFEEEVCK 200
    NLGLKAAPVS NQVIQRDRYA QVISAIAILA SSCEQIAVAI RHFQRTEVYE 250
    AEEYFSVGQK GSSAMPHKRN PVLSENITGL CRVLRSFVTP ALENVALWHE 300
    RDISHSSVER FILPDAFITA DFMLMRLTNL IDKLLVYPEN MMKNLNLTGG 350
    LVFSGRVLLE LPFKGISREE AYKIVQRNAM KVWADLQNGK AAINEKNESL 400
    FLLALLSDED LRKSLSEEDV RKCFDYNYYT KNVDAIFKRT FK 442
    Length:442
    Mass (Da):50,201
    Last modified:February 6, 2007 - v1
    Checksum:iBB6FDFEBE163D70F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000538 Genomic DNA. Translation: EAQ71984.1.
    RefSeqiYP_999743.1. NC_008787.1.

    Genome annotation databases

    EnsemblBacteriaiEAQ71984; EAQ71984; CJJ81176_0050.
    GeneIDi4682961.
    KEGGicjj:CJJ81176_0050.
    PATRICi20050048. VBICamJej103413_0074.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000538 Genomic DNA. Translation: EAQ71984.1 .
    RefSeqi YP_999743.1. NC_008787.1.

    3D structure databases

    ProteinModelPortali A1VXA2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 354242.CJJ81176_0050.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai EAQ71984 ; EAQ71984 ; CJJ81176_0050 .
    GeneIDi 4682961.
    KEGGi cjj:CJJ81176_0050.
    PATRICi 20050048. VBICamJej103413_0074.

    Phylogenomic databases

    eggNOGi COG0015.
    HOGENOMi HOG000033912.
    KOi K01756.
    OMAi RNMGSTF.
    OrthoDBi EOG686NDB.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00132 .
    UPA00075 ; UER00336 .
    BioCyci CJEJ354242:GC51-24-MONOMER.

    Family and domain databases

    Gene3Di 1.10.275.10. 1 hit.
    InterProi IPR019468. AdenyloSucc_lyase_C.
    IPR024083. Fumarase/histidase_N.
    IPR020557. Fumarate_lyase_CS.
    IPR000362. Fumarate_lyase_fam.
    IPR022761. Fumarate_lyase_N.
    IPR008948. L-Aspartase-like.
    IPR004769. Pur_lyase.
    [Graphical view ]
    PANTHERi PTHR11444. PTHR11444. 1 hit.
    Pfami PF10397. ADSL_C. 1 hit.
    PF00206. Lyase_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00149. FUMRATELYASE.
    SMARTi SM00998. ADSL_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48557. SSF48557. 1 hit.
    TIGRFAMsi TIGR00928. purB. 1 hit.
    PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Fouts D.E., Nelson K.E., Sebastian Y.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 81-176Imported.

    Entry informationi

    Entry nameiA1VXA2_CAMJJ
    AccessioniPrimary (citable) accession number: A1VXA2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 6, 2007
    Last sequence update: February 6, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3