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A1VUQ1 (PSD_POLNA) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:Pnap_4088
OrganismPolaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP]
Taxonomic identifier365044 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length289 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 250250Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000026562
Chain251 – 28939Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000026563

Sites

Site250 – 2512Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2511Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
A1VUQ1 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 747F000D5EBED966

FASTA28931,778
        10         20         30         40         50         60 
MSDRLAVLPQ YLLPKQALTH FAGFVASRER GWVTTEIIRR FVAKYRVNMS EALDSDIASY 

        70         80         90        100        110        120 
LTFNDFFTRA LKPGARPLAQ AALVCPVDGA ISQFGAIEHD QIFQAKGHHY STTALVGGDA 

       130        140        150        160        170        180 
ALAAHYQNGH FATIYLSPKD YHRIHMPCDG RLTRMIYVPG DLFSVNPVTA RGVPGLFARN 

       190        200        210        220        230        240 
ERVVCVFESA RGPFVLALVG ATIVGSMATV WHGVVNPPRG KAVREWRYPA SGQPEVVLRQ 

       250        260        270        280 
GEEMGRFLLG STVVLLFPKG PLRFNPDWEP GRAVRLGEAM ADVAADSQR

« Hide

References

[1]"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CJ2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000529 Genomic DNA. Translation: ABM39379.1.
RefSeqYP_984300.1. NC_008781.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA1VUQ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4687070.
GenomeReviewsGene locus Pnap_4088 in contig CP000529_GR.
KEGGpna:Pnap_4088.
PATRIC22952953. VBIPolNap76733_4992.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMASMATVWH.
PhylomeDBA1VUQ1.
ProtClustDBPRK00044.

Enzyme and pathway databases

BioCycPNAP365044:PNAP_4088-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_POLNA
AccessionPrimary (citable) accession number: A1VUQ1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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