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Protein

C4-dicarboxylate transport protein 2

Gene

dctA2

Organism
Polaromonas naphthalenivorans (strain CJ2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Enzyme and pathway databases

BioCyciPNAP365044:GJ8X-3803-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
C4-dicarboxylate transport protein 2UniRule annotation
Gene namesi
Name:dctA2UniRule annotation
Ordered Locus Names:Pnap_3748
OrganismiPolaromonas naphthalenivorans (strain CJ2)
Taxonomic identifieri365044 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
Proteomesi
  • UP000000644 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalUniRule annotationAdd
BLAST
Transmembranei49 – 6921HelicalUniRule annotationAdd
BLAST
Transmembranei81 – 10121HelicalUniRule annotationAdd
BLAST
Transmembranei149 – 16921HelicalUniRule annotationAdd
BLAST
Transmembranei193 – 21321HelicalUniRule annotationAdd
BLAST
Transmembranei227 – 24721HelicalUniRule annotationAdd
BLAST
Transmembranei294 – 31421HelicalUniRule annotationAdd
BLAST
Transmembranei335 – 35521HelicalUniRule annotationAdd
BLAST
Transmembranei357 – 37721HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 448448C4-dicarboxylate transport protein 2PRO_5000211347Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi365044.Pnap_3748.

Structurei

3D structure databases

ProteinModelPortaliA1VTR6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiFDFIEKF.
OrthoDBiEOG69GZN1.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1VTR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKTNARKPI YKSLYVQVLA AVTIGVLLGH FSPELGAQMK PLGDGFIKLI
60 70 80 90 100
KMIIAPIIFC TVVIGIAGME DMKKVGKTGG LALLYFEVMS TLALVIGLIV
110 120 130 140 150
VNVLQPGSGM HIDPASLDTK SIAAYTAPGK MQGTVDFLLN VIPTSVVDAF
160 170 180 190 200
AKGEILQVLL FSVLFGFALH RFGGRGTMVF DFIEKFSHVL FDIVGIIMKV
210 220 230 240 250
APIGAFGAMA FTIGKYGLGS LFSLGKLMGA FYLTCLIFVF VVLGIVSRLH
260 270 280 290 300
GFSVFKFVRY IKEELLIVLG TSSSESVLPR MMEKLENLGA RKSVVGLVIP
310 320 330 340 350
TGYSFNLDGT SIYLTMAAVF IAQATDTPMS LTQQITLLAV LMLTSKGAAG
360 370 380 390 400
ITGSGFIVLA ATLSAVGGVP VAGLALILGI DRFMSEARAL TNLVGNGVAT
410 420 430 440
LVVAKWTGDL DMQRLHQGLD QPSLQESQEP EVILDQQVAH MAVAKSHG
Length:448
Mass (Da):47,615
Last modified:February 6, 2007 - v1
Checksum:i80D42FFEB1D22402
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA. Translation: ABM39044.1.
RefSeqiWP_011803110.1. NC_008781.1.

Genome annotation databases

EnsemblBacteriaiABM39044; ABM39044; Pnap_3748.
KEGGipna:Pnap_3748.
PATRICi22952257. VBIPolNap76733_4644.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA. Translation: ABM39044.1.
RefSeqiWP_011803110.1. NC_008781.1.

3D structure databases

ProteinModelPortaliA1VTR6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi365044.Pnap_3748.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM39044; ABM39044; Pnap_3748.
KEGGipna:Pnap_3748.
PATRICi22952257. VBIPolNap76733_4644.

Phylogenomic databases

eggNOGiENOG4105CK2. Bacteria.
COG1301. LUCA.
HOGENOMiHOG000208775.
KOiK11103.
OMAiFDFIEKF.
OrthoDBiEOG69GZN1.

Enzyme and pathway databases

BioCyciPNAP365044:GJ8X-3803-MONOMER.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
HAMAPiMF_01300. C4_dicarb_transport.
InterProiIPR023954. C4_dicarb_transport.
IPR001991. Na-dicarboxylate_symporter.
IPR018107. Na-dicarboxylate_symporter_CS.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
PROSITEiPS00713. NA_DICARBOXYL_SYMP_1. 1 hit.
PS00714. NA_DICARBOXYL_SYMP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CJ2.

Entry informationi

Entry nameiDCTA2_POLNA
AccessioniPrimary (citable) accession number: A1VTR6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 6, 2007
Last modified: May 11, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.