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Protein

C4-dicarboxylate transport protein 2

Gene

dctA2

Organism
Polaromonas naphthalenivorans (strain CJ2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSymport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
C4-dicarboxylate transport protein 2UniRule annotation
Gene namesi
Name:dctA2UniRule annotation
Ordered Locus Names:Pnap_3748
OrganismiPolaromonas naphthalenivorans (strain CJ2)
Taxonomic identifieri365044 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
Proteomesi
  • UP000000644 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei13 – 33HelicalUniRule annotationAdd BLAST21
Transmembranei49 – 69HelicalUniRule annotationAdd BLAST21
Transmembranei81 – 101HelicalUniRule annotationAdd BLAST21
Transmembranei149 – 169HelicalUniRule annotationAdd BLAST21
Transmembranei193 – 213HelicalUniRule annotationAdd BLAST21
Transmembranei227 – 247HelicalUniRule annotationAdd BLAST21
Transmembranei294 – 314HelicalUniRule annotationAdd BLAST21
Transmembranei335 – 355HelicalUniRule annotationAdd BLAST21
Transmembranei357 – 377HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_50002113471 – 448C4-dicarboxylate transport protein 2Add BLAST448

Interactioni

Protein-protein interaction databases

STRINGi365044.Pnap_3748

Structurei

3D structure databases

ProteinModelPortaliA1VTR6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CK2 Bacteria
COG1301 LUCA
HOGENOMiHOG000208775
KOiK11103
OMAiHIDTRIT
OrthoDBiPOG091H06ON

Family and domain databases

Gene3Di1.10.3860.10, 1 hit
HAMAPiMF_01300 C4_dicarb_transport, 1 hit
InterProiView protein in InterPro
IPR023954 C4_dicarb_transport
IPR001991 Na-dicarboxylate_symporter
IPR018107 Na-dicarboxylate_symporter_CS
IPR036458 Na:dicarbo_symporter_sf
PfamiView protein in Pfam
PF00375 SDF, 1 hit
SUPFAMiSSF118215 SSF118215, 1 hit
PROSITEiView protein in PROSITE
PS00713 NA_DICARBOXYL_SYMP_1, 1 hit
PS00714 NA_DICARBOXYL_SYMP_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1VTR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKTNARKPI YKSLYVQVLA AVTIGVLLGH FSPELGAQMK PLGDGFIKLI
60 70 80 90 100
KMIIAPIIFC TVVIGIAGME DMKKVGKTGG LALLYFEVMS TLALVIGLIV
110 120 130 140 150
VNVLQPGSGM HIDPASLDTK SIAAYTAPGK MQGTVDFLLN VIPTSVVDAF
160 170 180 190 200
AKGEILQVLL FSVLFGFALH RFGGRGTMVF DFIEKFSHVL FDIVGIIMKV
210 220 230 240 250
APIGAFGAMA FTIGKYGLGS LFSLGKLMGA FYLTCLIFVF VVLGIVSRLH
260 270 280 290 300
GFSVFKFVRY IKEELLIVLG TSSSESVLPR MMEKLENLGA RKSVVGLVIP
310 320 330 340 350
TGYSFNLDGT SIYLTMAAVF IAQATDTPMS LTQQITLLAV LMLTSKGAAG
360 370 380 390 400
ITGSGFIVLA ATLSAVGGVP VAGLALILGI DRFMSEARAL TNLVGNGVAT
410 420 430 440
LVVAKWTGDL DMQRLHQGLD QPSLQESQEP EVILDQQVAH MAVAKSHG
Length:448
Mass (Da):47,615
Last modified:February 6, 2007 - v1
Checksum:i80D42FFEB1D22402
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA Translation: ABM39044.1
RefSeqiWP_011803110.1, NC_008781.1

Genome annotation databases

EnsemblBacteriaiABM39044; ABM39044; Pnap_3748
KEGGipna:Pnap_3748

Similar proteinsi

Entry informationi

Entry nameiDCTA2_POLNA
AccessioniPrimary (citable) accession number: A1VTR6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health