Skip Header

Contribute Send feedback
Read comments (?) or add your own

A1VTJ8 (A1VTJ8_POLNA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Isocitrate dehydrogenase, NADP-dependent EMBL ABM38976.1
EC=1.1.1.42 EMBL ABM38976.1
Gene names
Ordered Locus Names:Pnap_3680 EMBL ABM38976.1
OrganismPolaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP] EMBL ABM38976.1
Taxonomic identifier365044 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas ›

Protein attributes

Sequence length745 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region134 – 1418Substrate binding By similarity PIRSR PIRSR009407-2

Sites

Metal binding3521Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5511Magnesium or manganese By similarity PIRSR PIRSR009407-3
Metal binding5551Magnesium or manganese By similarity PIRSR PIRSR009407-3
Binding site1471Substrate By similarity PIRSR PIRSR009407-2
Binding site5501Substrate By similarity PIRSR PIRSR009407-2
Site2571Critical for catalysis By similarity PIRSR PIRSR009407-1
Site4221Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

Sequence LengthMass (Da)Tools
A1VTJ8 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: FA1F3F6567DD1086

FASTA74582,437
        10         20         30         40         50         60 
MTAGKSKIIY TLTDEAPLLA TWSFLPVVRA FTAPAGIEVA ESDISVAARV LAEFPEFLSD 

        70         80         90        100        110        120 
AQKVPNTLAE LGRLTQDPDT NIIKLPNISA SQGQLVSAIK ELQSKGFNLP DYPESPKSDE 

       130        140        150        160        170        180 
DKAIRARYAR CIGSSVNPVL REGNSDRRAP LAVKNYARKN PHSMADWSQA SRSHVSHMHH 

       190        200        210        220        230        240 
GDFYHGEKSM TLDKARDVKM ELITKSGKTI VLKPLTKLLD REVIDSMFMS KKELLDFYEQ 

       250        260        270        280        290        300 
EIDDAYKTGV MFSLHVKATM MKVSHPIVFG HCVKIFYKDA FEKHAKLFDE LGVNVNNGMA 

       310        320        330        340        350        360 
NLYDKISTLP QSTQDEIKRD LHACHEHRPE LAMVDSAKGI TNFHSPNDVI VDASMPAMIR 

       370        380        390        400        410        420 
NGGKMWGADG RLKDVKAVMP ESTFARIYQE IINFCKWHGA FDPKTMGTVP NVGLMAQQAE 

       430        440        450        460        470        480 
EYGSHDKTFE ISEDGVANIT DVATGEVLLS QNVEAGDIWR MCQCKDAAIR DWVKLAVNRA 

       490        500        510        520        530        540 
RNSGMPVVFW LDAYRPHEAQ LITKVKMYLH EHNTSGLDIQ IMSQVRAMRY TLERVVRGQD 

       550        560        570        580        590        600 
TISATGNILR DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVQQLVEEN 

       610        620        630        640        650        660 
HLRWDSLGEF LALAVSLEDL GIKTGNDQAK LLAKTLDAAT GKLLDNNKGP KTRTGELDNR 

       670        680        690        700        710        720 
GSHFYLAMYW AQALAEQTQD AALQARFAPL AKSLAENEAQ IVAEFKEVQG KPVDIGGYYL 

       730        740 
LDAEKVKAVM RPSATFNAVL SAAQA

« Hide

References

[1]"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CJ2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000529 Genomic DNA. Translation: ABM38976.1.
RefSeqYP_983897.1. NC_008781.1.

3D structure databases

ProteinModelPortalA1VTJ8.
SMRA1VTJ8. Positions 7-741.
ModBaseSearch...

Protein-protein interaction databases

STRING365044.Pnap_3680.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM38976; ABM38976; Pnap_3680.
GeneID4689721.
KEGGpna:Pnap_3680.
PATRIC22952113. VBIPolNap76733_4572.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2838.
HOGENOMHOG000240860.
KOK00031.
OMAPRTMGTV.
ProtClustDBCLSK867411.

Enzyme and pathway databases

BioCycPNAP365044:GJ8X-3735-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 3 hits.
InterProIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamPF03971. IDH. 1 hit.
[Graphical view]
PIRSFPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsTIGR00178. monomer_idh. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1VTJ8_POLNA
AccessionPrimary (citable) accession number: A1VTJ8
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info