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A1VTJ8

- A1VTJ8_POLNA

UniProt

A1VTJ8 - A1VTJ8_POLNA

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Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Pnap_3680

Organism
Polaromonas naphthalenivorans (strain CJ2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei257 – 2571Critical for catalysisUniRule annotation
Metal bindingi352 – 3521Magnesium or manganeseUniRule annotation
Sitei422 – 4221Critical for catalysisUniRule annotation
Binding sitei550 – 5501SubstrateUniRule annotation
Metal bindingi551 – 5511Magnesium or manganeseUniRule annotation
Metal bindingi555 – 5551Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPNAP365044:GJ8X-3735-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:Pnap_3680Imported
OrganismiPolaromonas naphthalenivorans (strain CJ2)Imported
Taxonomic identifieri365044 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
ProteomesiUP000000644: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi365044.Pnap_3680.

Structurei

3D structure databases

ProteinModelPortaliA1VTJ8.
SMRiA1VTJ8. Positions 7-741.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2838.
HOGENOMiHOG000240860.
KOiK00031.
OMAiSIVKLMQ.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

A1VTJ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAGKSKIIY TLTDEAPLLA TWSFLPVVRA FTAPAGIEVA ESDISVAARV
60 70 80 90 100
LAEFPEFLSD AQKVPNTLAE LGRLTQDPDT NIIKLPNISA SQGQLVSAIK
110 120 130 140 150
ELQSKGFNLP DYPESPKSDE DKAIRARYAR CIGSSVNPVL REGNSDRRAP
160 170 180 190 200
LAVKNYARKN PHSMADWSQA SRSHVSHMHH GDFYHGEKSM TLDKARDVKM
210 220 230 240 250
ELITKSGKTI VLKPLTKLLD REVIDSMFMS KKELLDFYEQ EIDDAYKTGV
260 270 280 290 300
MFSLHVKATM MKVSHPIVFG HCVKIFYKDA FEKHAKLFDE LGVNVNNGMA
310 320 330 340 350
NLYDKISTLP QSTQDEIKRD LHACHEHRPE LAMVDSAKGI TNFHSPNDVI
360 370 380 390 400
VDASMPAMIR NGGKMWGADG RLKDVKAVMP ESTFARIYQE IINFCKWHGA
410 420 430 440 450
FDPKTMGTVP NVGLMAQQAE EYGSHDKTFE ISEDGVANIT DVATGEVLLS
460 470 480 490 500
QNVEAGDIWR MCQCKDAAIR DWVKLAVNRA RNSGMPVVFW LDAYRPHEAQ
510 520 530 540 550
LITKVKMYLH EHNTSGLDIQ IMSQVRAMRY TLERVVRGQD TISATGNILR
560 570 580 590 600
DYLTDLFPIM ELGTSAKMLS IVPLMAGGGM YETGAGGSAP KHVQQLVEEN
610 620 630 640 650
HLRWDSLGEF LALAVSLEDL GIKTGNDQAK LLAKTLDAAT GKLLDNNKGP
660 670 680 690 700
KTRTGELDNR GSHFYLAMYW AQALAEQTQD AALQARFAPL AKSLAENEAQ
710 720 730 740
IVAEFKEVQG KPVDIGGYYL LDAEKVKAVM RPSATFNAVL SAAQA
Length:745
Mass (Da):82,437
Last modified:February 6, 2007 - v1
Checksum:iFA1F3F6567DD1086
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA. Translation: ABM38976.1.
RefSeqiWP_011803042.1. NC_008781.1.
YP_983897.1. NC_008781.1.

Genome annotation databases

EnsemblBacteriaiABM38976; ABM38976; Pnap_3680.
GeneIDi4689721.
KEGGipna:Pnap_3680.
PATRICi22952113. VBIPolNap76733_4572.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA. Translation: ABM38976.1 .
RefSeqi WP_011803042.1. NC_008781.1.
YP_983897.1. NC_008781.1.

3D structure databases

ProteinModelPortali A1VTJ8.
SMRi A1VTJ8. Positions 7-741.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 365044.Pnap_3680.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM38976 ; ABM38976 ; Pnap_3680 .
GeneIDi 4689721.
KEGGi pna:Pnap_3680.
PATRICi 22952113. VBIPolNap76733_4572.

Phylogenomic databases

eggNOGi COG2838.
HOGENOMi HOG000240860.
KOi K00031.
OMAi SIVKLMQ.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci PNAP365044:GJ8X-3735-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CJ2Imported.

Entry informationi

Entry nameiA1VTJ8_POLNA
AccessioniPrimary (citable) accession number: A1VTJ8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: November 26, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3