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A1VRJ4 (A1VRJ4_POLNA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Pnap_2973
OrganismPolaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP]
Taxonomic identifier365044 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2131Iron By similarity HAMAP MF_00323
Metal binding2941Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A1VRJ4 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: D0BFA422F2B4471C

FASTA36740,838
        10         20         30         40         50         60 
MSFAPEPTFT HGAPPKALAT TAILLCNLGT PDEPTAPALR RYLGEFLSDA RVVEIPRAIW 

        70         80         90        100        110        120 
WLILHGIILR TRPKKSAAKY ASVWLPEGSP LKVWTEKQAL MLRGYLGKRG HAVEVRYAMR 

       130        140        150        160        170        180 
YGNPSIASQL DQLKADGVTR VLILPAYPQY SGTTTASVFD AVYTWAAKIR RIPEFRFINH 

       190        200        210        220        230        240 
YHDDPGYIAA LADKIRRHWQ QSGQAEQLVM SFHGVPERTL HLGDPYHCEC QKTARLLADK 

       250        260        270        280        290        300 
LALPKDRYKV TFQSRFGKAK WLEPYTEPTL VQMARSGVKS VDVVCPGFTG DCLETLEEIN 

       310        320        330        340        350        360 
MEARHAFLEA GGKAFSYIEC LNDSPQWLAA LSELGLRHMG GWPTAAPAEP QALGDSRARA 


LALGAKQ

« Hide

References

[1]"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CJ2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000529 Genomic DNA. Translation: ABM38272.1.
RefSeqYP_983193.1. NC_008781.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA1VRJ4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4687235.
GenomeReviewsGene locus Pnap_2973 in contig CP000529_GR.
KEGGpna:Pnap_2973.
PATRIC22950647. VBIPolNap76733_3847.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBA1VRJ4.
ProtClustDBCLSK951224.

Enzyme and pathway databases

BioCycPNAP365044:PNAP_2973-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1VRJ4_POLNA
AccessionPrimary (citable) accession number: A1VRJ4
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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