A1VQI3 (GLMM_POLNA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Pnap_2609

Organism

Polaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP]

Taxonomic identifier

365044 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 443	443	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301353
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1VQI3 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: EFABE6A480DEA79D	FASTA	443	47,567
	10 20 30 40 50 60 MNRKYFGTDG IRGTVGEAPI TPDFVLRLAH AVGRVLRRTE ARPTVLIGKD TRISGYMLES 70 80 90 100 110 120 ALESGFNSAG VDVVLLGPLP TPGVAYLTRA QRASLGVVIS ASHNPFADNG IKFFSAQGNK 130 140 150 160 170 180 LNDEWEFEVE ATLKEEPVWA DSASLGKTRR LDDAAGRYIE FCKSTFAHDL TLKGLKIVVD 190 200 210 220 230 240 GAHGAAYQIA PMVFHELGAE VIAIGCAPDG LNINDGVGAT HPQALVNAVL ANKADYGIAL 250 260 270 280 290 300 DGDADRLQMV DAQGRLFNGD EVLYLMVNER LSRGEKVPGT VGTLMTNMAV EVALKAKGVE 310 320 330 340 350 360 FVRAKVGDRY ILEELERRGW LLGGEGSGHM LALDKHTTGD GLISALQVLQ ACARSNQTLA 370 380 390 400 410 420 QLLSEVVLFP QTLINVRLKP GQDWKNSAEL AAQTKAAEIE LGDSGRILIR ASGTEPLLRV 430 440 MVEARDAEQA RACAERVADA VRS

References

[1]

"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CJ2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000529 Genomic DNA. Translation: ABM37911.1.
RefSeq	YP_982832.1. NC_008781.1.
3D structure databases
ProteinModelPortal	A1VQI3.
ModBase	Search...
Protein-protein interaction databases
STRING	A1VQI3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4690087.
GenomeReviews	Gene locus Pnap_2609 in contig CP000529_GR.
KEGG	pna:Pnap_2609.
PATRIC	22949887. VBIPolNap76733_3476.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	ESTDNIM.
PhylomeDB	A1VQI3.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	PNAP365044:PNAP_2609-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_POLNA

Accession

Primary (citable) accession number: A1VQI3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	February 6, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program