Skip Header

Contribute Send feedback
Read comments (?) or add your own

A1VPA7 (A1VPA7_POLNA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Amino-acid acetyltransferase HAMAP MF_01105
EC=2.3.1.1 HAMAP MF_01105
Alternative name(s):
N-acetylglutamate synthase HAMAP MF_01105
Gene names
Name:argA HAMAP MF_01105
Ordered Locus Names:Pnap_2177
OrganismPolaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP]
Taxonomic identifier365044 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length450 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01105 SAAS SAAS010167

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01105 SAAS SAAS010167

Subcellular location

Cytoplasm By similarity HAMAP MF_01105 SAAS SAAS010167.

Miscellaneous

In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role By similarity. HAMAP MF_01105

Sequence similarities

Belongs to the acetyltransferase family. ArgA subfamily. HAMAP MF_01105

Contains 1 N-acetyltransferase domain. HAMAP MF_01105 SAAS SAAS010167

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain302 – 438137N-acetyltransferase By similarity HAMAP MF_01105

Sequences

Sequence LengthMass (Da)Tools
A1VPA7 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 05DDFC4B9505ABAE

FASTA45049,539
        10         20         30         40         50         60 
MSTVFNFTFV PWFRSVAPYI HKFRNQTFVV AVCGEAIAAG KLPHLAQDLA MIQSMGVKVV 

        70         80         90        100        110        120 
LVHGFRPQVN EQLRAKGHQA RYSHGMRITD EVALDCAQEA AGQLRYEIEA AFSQGLPNTP 

       130        140        150        160        170        180 
MAGSTIRVIS GNFITARPVG IVDGVDFQHS GLVRKVDVAG ITRTLDMGAM VLLSPFGFSP 

       190        200        210        220        230        240 
TGEAFNLTME EVATSVSIAL QADKLIFVTE VPGIRLKPGE PASEDNPIDT ELPLAAAEEL 

       250        260        270        280        290        300 
LSKAPPSQRP TDTAFYLQHC VKACKAGVER SHIIPFAVDG ALLLEIYVHD GIGTMVVDEK 

       310        320        330        340        350        360 
LEELREATAD DVGGILQLIE PFEKDGTLVK RSRTEIERDA DHYTIVEHDG VIFACAALYP 

       370        380        390        400        410        420 
YPEAKTAEMA ALTVSPQSQG QGDGEKILKR IEQRARAAGL QSIFVLTTRT MHWFIKRGFV 

       430        440        450 
QVDPDWLPDA RKRKYNWDRK SQVLVKKLQS

« Hide

References

[1]"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CJ2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000529 Genomic DNA. Translation: ABM37485.1.
RefSeqYP_982406.1. NC_008781.1.

3D structure databases

ProteinModelPortalA1VPA7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1VPA7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4687042.
GenomeReviewsGene locus Pnap_2177 in contig CP000529_GR.
KEGGpna:Pnap_2177.
PATRIC22949026. VBIPolNap76733_3049.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0548.
HOGENOMHBG545264.
OMAAFNLAME.
PhylomeDBA1VPA7.
ProtClustDBPRK05279.

Enzyme and pathway databases

BioCycPNAP365044:PNAP_2177-MONOMER.

Family and domain databases

HAMAPMF_01105. N_acetyl_glu_synth.
[Tree]
InterProIPR000182. AcTrfase_GCN5-related_dom.
IPR016181. Acyl_CoA_acyltransferase.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR010167. NH2A_AcTrfase_ArgA.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
KOK14682.
PfamPF00696. AA_kinase. 1 hit.
PF00583. Acetyltransf_1. 1 hit.
[Graphical view]
PIRSFPIRSF000423. ArgA. 1 hit.
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMsTIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITEPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1VPA7_POLNA
AccessionPrimary (citable) accession number: A1VPA7
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info