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A1VN52 (A1VN52_POLNA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase HAMAP MF_00387
Short name=UDP-N-acetylglucosamine acyltransferase HAMAP MF_00387
EC=2.3.1.129 HAMAP MF_00387
Gene names
Name:lpxA HAMAP MF_00387
Ordered Locus Names:Pnap_1770
OrganismPolaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP]
Taxonomic identifier365044 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas

Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. HAMAP MF_00387 SAAS SAAS010137

Catalytic activity

(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. HAMAP MF_00387 SAAS SAAS010137

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. HAMAP MF_00387 SAAS SAAS010137

Subunit structure

Homotrimer By similarity. HAMAP MF_00387 SAAS SAAS010137

Subcellular location

Cytoplasm By similarity HAMAP MF_00387 SAAS SAAS010137.

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxA subfamily. HAMAP MF_00387

Sequences

Sequence LengthMass (Da)Tools
A1VN52 [UniParc].

Last modified February 6, 2007. Version 1.
Checksum: 42A085721AE9EBB6

FASTA27028,996
        10         20         30         40         50         60 
MTLPAAPAGI HATALVDPLA QLDSSVTVGP YTVIGPHVRI GAGTTIGAHC VIEGHTTIGS 

        70         80         90        100        110        120 
DNRIFHFNSL GAVPQDKKYA GEPCELVIGD RNTIREFCSF NIGSPGDLGV TRLGDDNWIM 

       130        140        150        160        170        180 
AYVHVAHDCT VGNQTIFANN TTLAGHVQVG DWVILGGFTG VHQFVRLGAH SFTAISSVLV 

       190        200        210        220        230        240 
ADLPPFVMCQ GQPAEARSMN FEGLRRRGFS ADRISAVKAM HKALYRDGLT LEQAKVRIGE 

       250        260        270 
LTEKHPDSGP DVQMMLSFLE QTSPRRGIVR

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References

[1]"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CJ2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000529 Genomic DNA. Translation: ABM37080.1.
RefSeqYP_982001.1. NC_008781.1.

3D structure databases

ProteinModelPortalA1VN52.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1VN52.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4688443.
GenomeReviewsGene locus Pnap_1770 in contig CP000529_GR.
KEGGpna:Pnap_1770.
PATRIC22948174. VBIPolNap76733_2629.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1043.
HOGENOMHBG659295.
OMAREFCTFN.
PhylomeDBA1VN52.
ProtClustDBPRK05289.

Enzyme and pathway databases

BioCycPNAP365044:PNAP_1770-MONOMER.

Family and domain databases

HAMAPMF_00387. LpxA.
[Tree]
InterProIPR001451. Hexapep_transf.
IPR010137. Lipid_A_lpxA.
IPR011004. Trimer_LpxA-like.
[Graphical view]
KOK00677.
PfamPF00132. Hexapep. 3 hits.
[Graphical view]
PIRSFPIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAMSSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMsTIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1VN52_POLNA
AccessionPrimary (citable) accession number: A1VN52
Entry history
Integrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info