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Protein

Small ribosomal subunit biogenesis GTPase RsgA

Gene

rsgA

Organism
Polaromonas naphthalenivorans (strain CJ2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi254ZincUniRule annotation1
Metal bindingi259ZincUniRule annotation1
Metal bindingi261ZincUniRule annotation1
Metal bindingi267ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi110 – 113GTPUniRule annotation4
Nucleotide bindingi170 – 178GTPUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation, RNA-binding, rRNA-bindingUniRule annotationSAAS annotation
Biological processRibosome biogenesisUniRule annotationSAAS annotation
LigandGTP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, ZincUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Small ribosomal subunit biogenesis GTPase RsgAUniRule annotation (EC:3.6.1.-UniRule annotation)
Gene namesi
Name:rsgAUniRule annotation
Ordered Locus Names:Pnap_1467Imported
OrganismiPolaromonas naphthalenivorans (strain CJ2)Imported
Taxonomic identifieri365044 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaePolaromonas
Proteomesi
  • UP000000644 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi365044.Pnap_1467.

Structurei

3D structure databases

ProteinModelPortaliA1VMA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 230CP-type G (guanine nucleotide-binding)InterPro annotationAdd BLAST171
Domaini71 – 228EngC GTPaseInterPro annotationAdd BLAST158

Sequence similaritiesi

Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105E06. Bacteria.
COG1162. LUCA.
HOGENOMiHOG000006957.
KOiK06949.
OMAiFRDCKHL.
OrthoDBiPOG091H01WX.

Family and domain databases

CDDicd04466. S1_YloQ_GTPase. 1 hit.
cd01854. YjeQ_EngC. 1 hit.
HAMAPiMF_01820. GTPase_RsgA. 1 hit.
InterProiView protein in InterPro
IPR030378. G_CP_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR004881. Ribosome_biogen_GTPase_RsgA.
IPR010914. RsgA_GTPase_dom.
IPR031944. RsgA_N.
PANTHERiPTHR32120. PTHR32120. 1 hit.
PfamiView protein in Pfam
PF03193. RsgA_GTPase. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00157. TIGR00157. 1 hit.
PROSITEiView protein in PROSITE
PS50936. ENGC_GTPASE. 1 hit.
PS51721. G_CP. 1 hit.

Sequencei

Sequence statusi: Complete.

A1VMA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVVAGFGRHV LVETESGQRL ICHPRGKKSQ VVVGDRIRWL PSQDEGTIEK
60 70 80 90 100
IEERSNLFYR QDEMRTKSFA ANLDQILILI AAEPEFSESQ LTRALIAAEA
110 120 130 140 150
ERIKPIIALN KSDLAEPFGR AWTKLAPYRA MGYQVLPLAI KPKTAAAPAN
160 170 180 190 200
DGQTAELMAL LHGKKTLVLG PSGAGKSSLT NLLVPQAKVL TAEISQALNS
210 220 230 240 250
GKHTTTSTTL YWVDEARTTA LIDSPGFQEF GLHHIDPMQL ANYMPDFKAH
260 270 280 290 300
AQDCKFYNCT HLHEPGCGVI SEVKSTVSAS SISANRYRLY SELFAELSQT

RY
Length:302
Mass (Da):33,313
Last modified:February 6, 2007 - v1
Checksum:i79B7B89F2939C4D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA. Translation: ABM36781.1.

Genome annotation databases

EnsemblBacteriaiABM36781; ABM36781; Pnap_1467.
KEGGipna:Pnap_1467.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000529 Genomic DNA. Translation: ABM36781.1.

3D structure databases

ProteinModelPortaliA1VMA3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi365044.Pnap_1467.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM36781; ABM36781; Pnap_1467.
KEGGipna:Pnap_1467.

Phylogenomic databases

eggNOGiENOG4105E06. Bacteria.
COG1162. LUCA.
HOGENOMiHOG000006957.
KOiK06949.
OMAiFRDCKHL.
OrthoDBiPOG091H01WX.

Family and domain databases

CDDicd04466. S1_YloQ_GTPase. 1 hit.
cd01854. YjeQ_EngC. 1 hit.
HAMAPiMF_01820. GTPase_RsgA. 1 hit.
InterProiView protein in InterPro
IPR030378. G_CP_dom.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
IPR004881. Ribosome_biogen_GTPase_RsgA.
IPR010914. RsgA_GTPase_dom.
IPR031944. RsgA_N.
PANTHERiPTHR32120. PTHR32120. 1 hit.
PfamiView protein in Pfam
PF03193. RsgA_GTPase. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00157. TIGR00157. 1 hit.
PROSITEiView protein in PROSITE
PS50936. ENGC_GTPASE. 1 hit.
PS51721. G_CP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA1VMA3_POLNA
AccessioniPrimary (citable) accession number: A1VMA3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: June 7, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.