A1VMA3 (A1VMA3_POLNA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Putative ribosome biogenesis GTPase RsgA HAMAP-Rule MF_01820
EC=3.6.1.- HAMAP-Rule MF_01820

Gene names

Name:	rsgA HAMAP-Rule MF_01820
Ordered Locus Names:	Pnap_1467 EMBL ABM36781.1

Organism

Polaromonas naphthalenivorans (strain CJ2) [Complete proteome] [HAMAP] EMBL ABM36781.1

Taxonomic identifier

365044 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Polaromonas › Polaromonas naphthalenivorans

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover By similarity. HAMAP-Rule MF_01820 SAAS SAAS010914
Cofactor	Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_01820 SAAS SAAS010914
Subunit structure	Monomer By similarity. Associates with ribosomes. SAAS SAAS010914 Monomer. Associates with ribosomes By similarity. HAMAP-Rule MF_01820
Sequence similarities	Belongs to the RsgA GTPase family. HAMAP-Rule MF_01820 Contains 1 engC GTPase domain. HAMAP-Rule MF_01820 SAAS SAAS010914

Ontologies

Keywords
Ligand	GTP-binding HAMAP-Rule MF_01820 SAAS SAAS010914 Metal-binding HAMAP-Rule MF_01820 SAAS SAAS010914 Nucleotide-binding Zinc HAMAP-Rule MF_01820 SAAS SAAS010914
Molecular function	Hydrolase HAMAP-Rule MF_01820 SAAS SAAS010914
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Domain	71 – 228	158	EngC GTPase By similarity HAMAP-Rule MF_01820
	Nucleotide binding	110 – 113	4	GTP By similarity HAMAP-Rule MF_01820
	Nucleotide binding	170 – 178	9	GTP By similarity HAMAP-Rule MF_01820
	Motif	254 – 267	14	Knuckle-like cysteine cluster By similarity HAMAP-Rule MF_01820
Sites
	Metal binding	254	1	Zinc By similarity HAMAP-Rule MF_01820
	Metal binding	259	1	Zinc By similarity HAMAP-Rule MF_01820
	Metal binding	261	1	Zinc By similarity HAMAP-Rule MF_01820
	Metal binding	267	1	Zinc By similarity HAMAP-Rule MF_01820

Sequences

	Sequence		Length	Mass (Da)
	A1VMA3 [UniParc]. Last modified February 6, 2007. Version 1. Checksum: 79B7B89F2939C4D9	FASTA	302	33,313
	10 20 30 40 50 60 MVVAGFGRHV LVETESGQRL ICHPRGKKSQ VVVGDRIRWL PSQDEGTIEK IEERSNLFYR 70 80 90 100 110 120 QDEMRTKSFA ANLDQILILI AAEPEFSESQ LTRALIAAEA ERIKPIIALN KSDLAEPFGR 130 140 150 160 170 180 AWTKLAPYRA MGYQVLPLAI KPKTAAAPAN DGQTAELMAL LHGKKTLVLG PSGAGKSSLT 190 200 210 220 230 240 NLLVPQAKVL TAEISQALNS GKHTTTSTTL YWVDEARTTA LIDSPGFQEF GLHHIDPMQL 250 260 270 280 290 300 ANYMPDFKAH AQDCKFYNCT HLHEPGCGVI SEVKSTVSAS SISANRYRLY SELFAELSQT RY

References

[1]

"Complete sequence of chromosome 1 of Polaromonas naphthalenivorans CJ2." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D.R., Brettin T., Bruce D., Han C., Tapia R., Brainard J., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Madsen E.L., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CJ2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000529 Genomic DNA. Translation: ABM36781.1.
RefSeq	YP_981702.1. NC_008781.1.
3D structure databases
ProteinModelPortal	A1VMA3.
ModBase	Search...
Protein-protein interaction databases
STRING	365044.Pnap_1467.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABM36781; ABM36781; Pnap_1467.
GeneID	4686513.
KEGG	pna:Pnap_1467.
PATRIC	22947541. VBIPolNap76733_2320.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1162.
HOGENOM	HOG000006957.
KO	K06949.
OMA	CFIEFRD.
Enzyme and pathway databases
BioCyc	PNAP365044:GJ8X-1487-MONOMER.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
HAMAP	MF_01820. GTPase_RsgA.
InterPro	IPR010914. EngC_GTPase. IPR012340. NA-bd_OB-fold. IPR004881. Ribosome_biogen_GTPase_RsgA. [Graphical view]
Pfam	PF03193. DUF258. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00157. TIGR00157. 1 hit.
PROSITE	PS50936. ENGC_GTPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1VMA3_POLNA

Accession

Primary (citable) accession number: A1VMA3

Entry history

Integrated into UniProtKB/TrEMBL:	February 6, 2007
Last sequence update:	February 6, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)