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Protein

Glutamyl-tRNA(Gln) amidotransferase subunit A

Gene

gatA

Organism
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei78Charge relay systemUniRule annotation1
Active sitei153Charge relay systemUniRule annotation1
Active sitei177Acyl-ester intermediateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation (EC:6.3.5.7UniRule annotation)
Short name:
Glu-ADT subunit AUniRule annotation
Gene namesi
Name:gatAUniRule annotation
Ordered Locus Names:Dvul_2169
OrganismiDesulfovibrio vulgaris subsp. vulgaris (strain DP4)
Taxonomic identifieri391774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000009173 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000158281 – 489Glutamyl-tRNA(Gln) amidotransferase subunit AAdd BLAST489

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA1VFG9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the amidase family. GatA subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000116699.
KOiK02433.
OMAiKEYFGAG.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1VFG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALHTLSLA AIRDALARRE VRAEDAVLDC LARIETTEPR IDALLHLRAE
60 70 80 90 100
AAIEEARALD AAGPDASRPL WGVPVTVKDA LTTAGTPTTA GSRILEDFVP
110 120 130 140 150
FYDAFAVQRL REAGAIILGK NNMDEFAMGS STENSAYKPT RNPWDTARVP
160 170 180 190 200
GGSSGGSAAS VAAGQCFASL GTDTGGSIRQ PASLCGCVGL KPTYGRVSRF
210 220 230 240 250
GLIAYGSSLD QIGPMTRTVE DAAIVMGVIA GHDKRDSTCA DRPVEDFAAA
260 270 280 290 300
LASRHDLAGV RIGVPAEFWG EGLSPEVATS CRAALDAARD LGATIVDVAL
310 320 330 340 350
PHTPQSIAAY YIVASAEASS NLARYDGVRY GKRAHAPEDL MDLYVRSRSE
360 370 380 390 400
GLGDEVQRRI MLGTYVLSSG YYDAYYRKAA QVRRRILEDY RNAFATCDVI
410 420 430 440 450
CGPVSPVTAW PLGALTADPL QMYLMDVFTL SLNLAGLPGL SLPVGLGTES
460 470 480
GMPVGIQLLG RSFDEATLLS VGNVLSRALP PLGSPAGLR
Length:489
Mass (Da):51,621
Last modified:February 6, 2007 - v1
Checksum:i5DB1E7B633CF6D7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA. Translation: ABM29185.1.
RefSeqiWP_011792698.1. NC_008751.1.

Genome annotation databases

EnsemblBacteriaiABM29185; ABM29185; Dvul_2169.
KEGGidvl:Dvul_2169.
PATRICi21768250. VBIDesVul62463_2394.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA. Translation: ABM29185.1.
RefSeqiWP_011792698.1. NC_008751.1.

3D structure databases

ProteinModelPortaliA1VFG9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM29185; ABM29185; Dvul_2169.
KEGGidvl:Dvul_2169.
PATRICi21768250. VBIDesVul62463_2394.

Phylogenomic databases

HOGENOMiHOG000116699.
KOiK02433.
OMAiKEYFGAG.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA. 1 hit.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGATA_DESVV
AccessioniPrimary (citable) accession number: A1VFG9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.