Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

30S ribosomal protein S12

Gene

rpsL

Organism
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

With S4 and S5 plays an important role in translational accuracy.UniRule annotation
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciDVUL391774:GHS0-1826-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S12UniRule annotation
Gene namesi
Name:rpsLUniRule annotation
Ordered Locus Names:Dvul_1770
OrganismiDesulfovibrio vulgaris subsp. vulgaris (strain DP4)
Taxonomic identifieri391774 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000009173 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12312330S ribosomal protein S12PRO_0000295970Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei89 – 8913-methylthioaspartic acidBy similarity

Keywords - PTMi

Methylation

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA1VEC1.
SMRiA1VEC1. Positions 3-123.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S12P family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000040063.
KOiK02950.
OMAiLKSCPER.

Family and domain databases

CDDicd03368. Ribosomal_S12. 1 hit.
Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00403_B. Ribosomal_S12_B. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1VEC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTINQLIRK ERKKVVKRKK TPALQACPQR RGVCTRVYTT TPKKPNSALR
60 70 80 90 100
KVARVRLTNG LEVTAYIPGE GHNLQEHSVV MIRGGRVKDL PGVRYHIVRG
110 120
TLDTSGVQDR RQGRSKYGAK RPK
Length:123
Mass (Da):13,909
Last modified:February 6, 2007 - v1
Checksum:i5281DBC60B35CD66
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA. Translation: ABM28787.1.
RefSeqiWP_010938593.1. NC_008751.1.

Genome annotation databases

EnsemblBacteriaiABM28787; ABM28787; Dvul_1770.
KEGGidvl:Dvul_1770.
PATRICi21767416. VBIDesVul62463_1982.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000527 Genomic DNA. Translation: ABM28787.1.
RefSeqiWP_010938593.1. NC_008751.1.

3D structure databases

ProteinModelPortaliA1VEC1.
SMRiA1VEC1. Positions 3-123.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM28787; ABM28787; Dvul_1770.
KEGGidvl:Dvul_1770.
PATRICi21767416. VBIDesVul62463_1982.

Phylogenomic databases

HOGENOMiHOG000040063.
KOiK02950.
OMAiLKSCPER.

Enzyme and pathway databases

BioCyciDVUL391774:GHS0-1826-MONOMER.

Family and domain databases

CDDicd03368. Ribosomal_S12. 1 hit.
Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00403_B. Ribosomal_S12_B. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS12_DESVV
AccessioniPrimary (citable) accession number: A1VEC1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: February 6, 2007
Last modified: September 7, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.